Basic principles of synthesis and conformational analysis of acetylene and biologically active compounds

Isobaev, Muzafar J., Fayzilov, Ikrom U., Abdullaev, Tokhir Kh., Pulatov, Elmurod Kh.

Товарлар кимёси ва халқ табобати · 2025-yil

Annotatsiya

The article focuses on the synthesis of enyne triols and their stereochemical and conformational features. The preparation of Z- and E-isomers, their separation, and structural confirmation through spectroscopic methods are described. Analysis of NMR spectra and anisotropy calculations revealed conformational differences between the isomers. Pharmacological studies demonstrated that the synthesized enyne triols exhibit significant choleretic activity, with E-isomers being more active than Z-isomers. These findings highlight the potential of enyne triols as promising candidates for the development of new therapeutic agents.

Maqola ma’lumotlari
MualliflarIsobaev, Muzafar J., Fayzilov, Ikrom U., Abdullaev, Tokhir Kh., Pulatov, Elmurod Kh.
JurnalТоварлар кимёси ва халқ табобати
NashriyotТабобат академияси
ISSN2181-2977
Nashr sanasi2025-11-11
Jild4
Son3
Betlar56-67
TilIngliz
Ilmiy sohaKimyo
DOI10.55475/jcgtm/vol4.iss3.2025.524
Indeksga qo‘shilgan2026-08-26

DOI: 10.55475/jcgtm/vol4.iss3.2025.524 · Maqolaning asl sahifasi

Kalit so‘zlar

organic chemistry, enyne triols, Z/E-isomerism, conformation, NMR spectroscopy, anisotropy, choleretic activity, органическая химия, енинтриолы, Z/E-изомерия, конформация, ЯМР-спектроскопия, анизотропия, холеретическая активность, organik kimyo, enin triollar, Z/E-izomeriya, konformatsiya, NMR spektroskopiya, xemotropiya, xoliyeretik faollik

Ilmiy soha

Kimyo

Iqtibos keltirish

APAIsobaev, Muzafar J., Fayzilov, Ikrom U., Abdullaev, Tokhir Kh., & Pulatov, Elmurod Kh. (2025). BASIC PRINCIPLES OF SYNTHESIS AND CONFORMATIONAL ANALYSIS OF ACETYLENE AND BIOLOGICALLY ACTIVE COMPOUNDS. Товарлар кимёси ва халқ табобати, 4(3), 56-67. https://doi.org/10.55475/jcgtm/vol4.iss3.2025.524
GOST (OAK)Isobaev, Muzafar J. va b. BASIC PRINCIPLES OF SYNTHESIS AND CONFORMATIONAL ANALYSIS OF ACETYLENE AND BIOLOGICALLY ACTIVE COMPOUNDS // Товарлар кимёси ва халқ табобати. – 2025. – T. 4, № 3. – P. 56-67. – DOI: 10.55475/jcgtm/vol4.iss3.2025.524.
MLAIsobaev, Muzafar J., Fayzilov, Ikrom U., Abdullaev, Tokhir Kh., and Pulatov, Elmurod Kh. “BASIC PRINCIPLES OF SYNTHESIS AND CONFORMATIONAL ANALYSIS OF ACETYLENE AND BIOLOGICALLY ACTIVE COMPOUNDS.” Товарлар кимёси ва халқ табобати, 4(3), 56-67, 2025. https://doi.org/10.55475/jcgtm/vol4.iss3.2025.524
ChicagoIsobaev, Muzafar J., Fayzilov, Ikrom U., Abdullaev, Tokhir Kh., and Pulatov, Elmurod Kh. “BASIC PRINCIPLES OF SYNTHESIS AND CONFORMATIONAL ANALYSIS OF ACETYLENE AND BIOLOGICALLY ACTIVE COMPOUNDS.” Товарлар кимёси ва халқ табобати, 4(3), 56-67 (2025). https://doi.org/10.55475/jcgtm/vol4.iss3.2025.524
HarvardIsobaev, Muzafar J., Fayzilov, Ikrom U., Abdullaev, Tokhir Kh., and Pulatov, Elmurod Kh (2025) ‘BASIC PRINCIPLES OF SYNTHESIS AND CONFORMATIONAL ANALYSIS OF ACETYLENE AND BIOLOGICALLY ACTIVE COMPOUNDS’, Товарлар кимёси ва халқ табобати, 4(3), 56-67. https://doi.org/10.55475/jcgtm/vol4.iss3.2025.524
BibTeX
@article{isobaevmuzafarj2025,
  title = {BASIC PRINCIPLES OF SYNTHESIS AND CONFORMATIONAL ANALYSIS OF ACETYLENE AND BIOLOGICALLY ACTIVE COMPOUNDS},
  author = {Isobaev, Muzafar J. and Fayzilov, Ikrom U. and Abdullaev, Tokhir Kh. and Pulatov, Elmurod Kh.},
  journal = {Товарлар кимёси ва халқ табобати},
  year = {2025},
  volume = {4},
  number = {3},
  pages = {56-67},
  doi = {10.55475/jcgtm/vol4.iss3.2025.524},
  url = {https://doi.org/10.55475/jcgtm/vol4.iss3.2025.524}
}

Boshqa maqola uchun iqtibos tayyorlash

Товарлар кимёси ва халқ табобати jurnalidan boshqa maqolalar

Товарлар кимёси ва халқ табобати — barcha maqolalar · 2025-yil arxivi

Kimyo sohasidagi boshqa maqolalar

Kimyo sohasidagi OAK jurnallari