This study introduces novel approaches against multidrug-resistant bacteria using nanozymes and phosphatase inhibitors. Beet-derived SN-CNPs exhibited robust phosphatase-like activity and selectively disrupted bacterial membranes, while sodium orthovanadate (SOV) inhibited phosphatases essential for cell wall synthesis, exerting bactericidal effects. Combined application of SN-CNPs and SOV enhanced antimicrobial efficacy against E. coli and L. lactis, highlighting a synergistic mechanism. The findings underscore phosphatase-centered strategies as a paradigm shift from conventional ROS-dependent therapies and open new avenues for multi-targeted antimicrobial interventions.
| Mualliflar | Benassi, Enrico, Fan, Haiyan |
|---|---|
| Jurnal | Товарлар кимёси ва халқ табобати |
| Nashriyot | Табобат академияси |
| ISSN | 2181-2977 |
| Nashr sanasi | 2025-11-11 |
| Jild | 4 |
| Son | 3 |
| Betlar | 68-77 |
| Til | Ingliz |
| Ilmiy soha | Tibbiyot |
| DOI | 10.55475/jcgtm/vol4.iss3.2025.530 |
| Indeksga qo‘shilgan | 2026-08-26 |
DOI: 10.55475/jcgtm/vol4.iss3.2025.530 · Maqolaning asl sahifasi
multidrug-resistant bacteria, nanozymes, phosphatase inhibitor, SN-CNP, SOV, synergy, antimicrobial therapy, множественная лекарственная устойчивость, нанозимы, ингибитор фосфатазы, SN-CNP, SOV, синергия, антимикробная терапия
| APA | Benassi, Enrico, & Fan, Haiyan (2025). INNOVATIVE ANTIMICROBIAL STRATEGIES USING CARBON NANOZYMES AND PHOSPHATASE INHIBITORS: SYNERGISTIC EFFECTS AND MECHANISTIC INSIGHTS. Товарлар кимёси ва халқ табобати, 4(3), 68-77. https://doi.org/10.55475/jcgtm/vol4.iss3.2025.530 |
|---|---|
| GOST (OAK) | Benassi, Enrico, Fan, Haiyan INNOVATIVE ANTIMICROBIAL STRATEGIES USING CARBON NANOZYMES AND PHOSPHATASE INHIBITORS: SYNERGISTIC EFFECTS AND MECHANISTIC INSIGHTS // Товарлар кимёси ва халқ табобати. – 2025. – T. 4, № 3. – P. 68-77. – DOI: 10.55475/jcgtm/vol4.iss3.2025.530. |
| MLA | Benassi, Enrico, and Fan, Haiyan. “INNOVATIVE ANTIMICROBIAL STRATEGIES USING CARBON NANOZYMES AND PHOSPHATASE INHIBITORS: SYNERGISTIC EFFECTS AND MECHANISTIC INSIGHTS.” Товарлар кимёси ва халқ табобати, 4(3), 68-77, 2025. https://doi.org/10.55475/jcgtm/vol4.iss3.2025.530 |
| Chicago | Benassi, Enrico, and Fan, Haiyan. “INNOVATIVE ANTIMICROBIAL STRATEGIES USING CARBON NANOZYMES AND PHOSPHATASE INHIBITORS: SYNERGISTIC EFFECTS AND MECHANISTIC INSIGHTS.” Товарлар кимёси ва халқ табобати, 4(3), 68-77 (2025). https://doi.org/10.55475/jcgtm/vol4.iss3.2025.530 |
| Harvard | Benassi, Enrico, and Fan, Haiyan (2025) ‘INNOVATIVE ANTIMICROBIAL STRATEGIES USING CARBON NANOZYMES AND PHOSPHATASE INHIBITORS: SYNERGISTIC EFFECTS AND MECHANISTIC INSIGHTS’, Товарлар кимёси ва халқ табобати, 4(3), 68-77. https://doi.org/10.55475/jcgtm/vol4.iss3.2025.530 |
| BibTeX | @article{benassienrico2025,
title = {INNOVATIVE ANTIMICROBIAL STRATEGIES USING CARBON NANOZYMES AND PHOSPHATASE INHIBITORS: SYNERGISTIC EFFECTS AND MECHANISTIC INSIGHTS},
author = {Benassi, Enrico and Fan, Haiyan},
journal = {Товарлар кимёси ва халқ табобати},
year = {2025},
volume = {4},
number = {3},
pages = {68-77},
doi = {10.55475/jcgtm/vol4.iss3.2025.530},
url = {https://doi.org/10.55475/jcgtm/vol4.iss3.2025.530}
} |
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