The purpose of the study is to perform the ultrasound Doppler of kidneys characteristics of patients with type 2 diabetes and stages of chronic kidney disease1-4 ” Material and research methods. In total, 80 patients with diabetes 2 and CKD 1-4, from the bottom of 47 men and 33 women were selected to study the effects of various nephroprotective therapy schemes on the functional state of the kidneys in type 2 diabetes 2, patients were divided into 4 therapeutic groups: 1 group amounted to 20 patients with diabetes 2 and CKD 1-4 dg. receiving SGLT-2 (EMAGLIF) + metformin 2 groups-amounted to 20 patients with diabetes 2 and CKD 1-4 dg. receiving SGLT-2 (EMAGLIF) + DPP 4 (Januvia) 3 group-amounted to 20 patients with diabetes 2 and CKD1-4 dg, receiving SGLT-2 (EMAGLIF) + GPP 1 (Victosa) 4 groups-amounted to-20 patients with diabetes 2 and CKD 1-4 dg, receiving SGLT-2 + insulin. In the work, general clinical, clinical and biochemical (Al, AST, bilirubin, bird, urea, creatinine, SKF, C-reactive protein, etc.), hormonal (insulin, s-peptide), immunological (uromodulin) methods of blood test, as well as instrumental methods of examination-uzi of internal organs, dopplerography of kidney vessels, as well as statistical methods. The control group amounted to 20 healthy persons. Research results. As the age increases in patients, the level of comorbidity is also increased. The initial data of carbohydrate metabolism indicated their reliable difference from the indicators of the norm (p <0.05). Indicators of the resistance index of the renal and segmental arteries increase as the functional impaired renal impairment progresses and reliably correlate with the main indicators of the functional activity of the kidneys. Conclusions: 1. As the age increases, the level of comorbidity increases. Thus, the highest level of comorbid pathology was observed in patients of the older age group (≥60 years): in 37.2% of patients of this group, the values of the level of comorbid pathology were 14-23 points. In patients with diabetes mellitus, 2 Tina with CKD 1-4 dg, there are changes in renal hemodynamics, which were manifested by an increase in intracranial vascular resistance at the level of renal, segmental and inter-lane arteries.
| Mualliflar | Хайдарова Ф.А, Тешабекова М.К |
|---|---|
| Jurnal | Марказий Осиё эндокринологик журнали |
| Nashr sanasi | 2022-12-23 |
| Jild | 2 |
| Son | 2 |
| Til | Rus |
сахарный диабет 2 тип, кардио-ренальный синдром, лечение, Qandli diabet 2 turi 2, kardio-renal sindromi, davolash, diabetes mellitus 2 type 2, cardio-renal syndrome, treatment
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