Results of experimental studies on the anti-adhesive activity of a hydrogel based on the sodium salt of carboxymethylcellullose

BILALOV Bakhodir Erkinovich, BILALOV Bakhodir Erkinovich, ORIPOV Okilkhon Ilyasovich

Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali · 2025-yil

Annotatsiya

Purpose of the study. To evaluate the antiproliferative effect of a Na-CMC (carboxymethylcellullose) hydrogel in modulating the adhesion process in the abdominal cavity using experimental models with white rats. Materials and methods. The experiment was conducted on 100 mature outbred female rats weighing 160-180 grams. The adhesion process in white rats was induced using a standard method: under general anesthesia, a midline laparotomy was performed, the cecum was brought out into the wound, and the adhesion process was modeled by deserosalizing the cecum with a gauze pad. Results: The study demonstrated that the use of Na-CMC-based hydrogels significantly reduces the severity of the adhesion process in the abdominal cavity. The 3.5% hydrogel, in particular, was found to be especially effective, showing the least severity of adhesions on both the 7th and 10th days. Conclusion: This study confirmed that Na-CMC-based hydrogels effectively reduce the severity of the adhesion process in the abdominal cavity.

Maqola ma’lumotlari
MualliflarBILALOV Bakhodir Erkinovich, BILALOV Bakhodir Erkinovich, ORIPOV Okilkhon Ilyasovich
JurnalJournal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali
NashriyotТошкент давлат стоматалогия институти, , «Expert Lawyers» MЧЖ
ISSN2181-9300
Nashr sanasi2025-11-03
Jild10
Son4
TilIngliz
Ilmiy sohaTibbiyot
Indeksga qo‘shilgan2026-08-27

Kalit so‘zlar

спаечный процесс в брюшной полости, гидрогель, карбоксиметилцеллюллоза., abdominal adhesions, hydrogel, carboxymethylcellullose, qorin bo'shlig'ida bitishmalar hosil boʻlish jarayoni, gidrogel, Natriy karboksimetiltsellyulloza (Na-CMS).

Ilmiy soha

Iqtibos keltirish

APABILALOV Bakhodir Erkinovich, BILALOV Bakhodir Erkinovich, & ORIPOV Okilkhon Ilyasovich (2025). RESULTS OF EXPERIMENTAL STUDIES ON THE ANTI-ADHESIVE ACTIVITY OF A HYDROGEL BASED ON THE SODIUM SALT OF CARBOXYMETHYLCELLULLOSE. Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 10(4). https://tadqiqot.uz/index.php/biomedicine/article/view/12767
GOST (OAK)BILALOV Bakhodir Erkinovich, BILALOV Bakhodir Erkinovich, ORIPOV Okilkhon Ilyasovich RESULTS OF EXPERIMENTAL STUDIES ON THE ANTI-ADHESIVE ACTIVITY OF A HYDROGEL BASED ON THE SODIUM SALT OF CARBOXYMETHYLCELLULLOSE // Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali. – 2025. – T. 10, № 4.
MLABILALOV Bakhodir Erkinovich, BILALOV Bakhodir Erkinovich, and ORIPOV Okilkhon Ilyasovich. “RESULTS OF EXPERIMENTAL STUDIES ON THE ANTI-ADHESIVE ACTIVITY OF A HYDROGEL BASED ON THE SODIUM SALT OF CARBOXYMETHYLCELLULLOSE.” Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 10(4), 2025. https://tadqiqot.uz/index.php/biomedicine/article/view/12767
ChicagoBILALOV Bakhodir Erkinovich, BILALOV Bakhodir Erkinovich, and ORIPOV Okilkhon Ilyasovich. “RESULTS OF EXPERIMENTAL STUDIES ON THE ANTI-ADHESIVE ACTIVITY OF A HYDROGEL BASED ON THE SODIUM SALT OF CARBOXYMETHYLCELLULLOSE.” Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 10(4) (2025). https://tadqiqot.uz/index.php/biomedicine/article/view/12767
HarvardBILALOV Bakhodir Erkinovich, BILALOV Bakhodir Erkinovich, and ORIPOV Okilkhon Ilyasovich (2025) ‘RESULTS OF EXPERIMENTAL STUDIES ON THE ANTI-ADHESIVE ACTIVITY OF A HYDROGEL BASED ON THE SODIUM SALT OF CARBOXYMETHYLCELLULLOSE’, Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 10(4). https://tadqiqot.uz/index.php/biomedicine/article/view/12767
BibTeX
@article{bilalovbakhodirerkinovich2025,
  title = {RESULTS OF EXPERIMENTAL STUDIES ON THE ANTI-ADHESIVE ACTIVITY OF A HYDROGEL BASED ON THE SODIUM SALT OF CARBOXYMETHYLCELLULLOSE},
  author = {BILALOV Bakhodir Erkinovich and BILALOV Bakhodir Erkinovich and ORIPOV Okilkhon Ilyasovich},
  journal = {Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali},
  year = {2025},
  volume = {10},
  number = {4},
  url = {https://tadqiqot.uz/index.php/biomedicine/article/view/12767}
}

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