The role of genetic studies in the diagnosis of various forms of thrombocytopenia in children (literature revie)

IRISKULOV Baxtier O‘ktamovich, IBRAGIMOVA Sapura Zaxidovna, XUSANOVA Diera Ziyadullaevna

Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali · 2025-yil

Annotatsiya

Immune thrombocytopenic purpura (ITP) is one of the most common immune hematopathies, in the development of which the leading role is played by antibodies directed against a narrow spectrum of platelet antigens. Despite the fact that mortality in chronic ITP is low (no more than 1%), the disease dramatically reduces the patient's quality of life and often requires complex and expensive treatment. A major problem is the diagnosis and treatment of chronic forms of the disease, under the guise of which hereditary thrombocytopenia or primary immunodeficiency (PID) can often be hidden. Recently, the use of high-throughput sequencing (HTS) has improved the diagnosis of hereditary thrombocytopenia. Using sequencing, 33 different forms of hereditary thrombocytopenia caused by molecular defects affecting at least 32 genes were identified; the pathogenetic mechanisms of thrombocytopenia were also studied in more detail and therapeutic options were developed.

Maqola ma’lumotlari
MualliflarIRISKULOV Baxtier O‘ktamovich, IBRAGIMOVA Sapura Zaxidovna, XUSANOVA Diera Ziyadullaevna
JurnalJournal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali
NashriyotТошкент давлат стоматалогия институти, , «Expert Lawyers» MЧЖ
ISSN2181-9300
Nashr sanasi2025-08-09
Jild10
Son3/1
TilIngliz
Ilmiy sohaTibbiyot
Indeksga qo‘shilgan2026-08-27

Maqolaning asl sahifasi

Kalit so‘zlar

Иммунная тромбоцитопения, дети, генетическое исследование, секвенирование нового поколения., Immune thrombocytopenia, children, genetic testing, next-generation sequencing., Immun trombotsitopeniya, bolalar, genetik test, keyingi avlod sekvensiyasi.

Ilmiy soha

Tibbiyot

Iqtibos keltirish

APAIRISKULOV Baxtier O‘ktamovich, IBRAGIMOVA Sapura Zaxidovna, & XUSANOVA Diera Ziyadullaevna (2025). THE ROLE OF GENETIC STUDIES IN THE DIAGNOSIS OF VARIOUS FORMS OF THROMBOCYTOPENIA IN CHILDREN (LITERATURE REVIE). Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 10(3/1). https://tadqiqot.uz/index.php/biomedicine/article/view/12046
GOST (OAK)IRISKULOV Baxtier O‘ktamovich, IBRAGIMOVA Sapura Zaxidovna, XUSANOVA Diera Ziyadullaevna THE ROLE OF GENETIC STUDIES IN THE DIAGNOSIS OF VARIOUS FORMS OF THROMBOCYTOPENIA IN CHILDREN (LITERATURE REVIE) // Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali. – 2025. – T. 10, № 3/1.
MLAIRISKULOV Baxtier O‘ktamovich, IBRAGIMOVA Sapura Zaxidovna, and XUSANOVA Diera Ziyadullaevna. “THE ROLE OF GENETIC STUDIES IN THE DIAGNOSIS OF VARIOUS FORMS OF THROMBOCYTOPENIA IN CHILDREN (LITERATURE REVIE).” Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 10(3/1), 2025. https://tadqiqot.uz/index.php/biomedicine/article/view/12046
ChicagoIRISKULOV Baxtier O‘ktamovich, IBRAGIMOVA Sapura Zaxidovna, and XUSANOVA Diera Ziyadullaevna. “THE ROLE OF GENETIC STUDIES IN THE DIAGNOSIS OF VARIOUS FORMS OF THROMBOCYTOPENIA IN CHILDREN (LITERATURE REVIE).” Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 10(3/1) (2025). https://tadqiqot.uz/index.php/biomedicine/article/view/12046
HarvardIRISKULOV Baxtier O‘ktamovich, IBRAGIMOVA Sapura Zaxidovna, and XUSANOVA Diera Ziyadullaevna (2025) ‘THE ROLE OF GENETIC STUDIES IN THE DIAGNOSIS OF VARIOUS FORMS OF THROMBOCYTOPENIA IN CHILDREN (LITERATURE REVIE)’, Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 10(3/1). https://tadqiqot.uz/index.php/biomedicine/article/view/12046
BibTeX
@article{iriskulovbaxtieroktamovich2025,
  title = {THE ROLE OF GENETIC STUDIES IN THE DIAGNOSIS OF VARIOUS FORMS OF THROMBOCYTOPENIA IN CHILDREN (LITERATURE REVIE)},
  author = {IRISKULOV Baxtier O‘ktamovich and IBRAGIMOVA Sapura Zaxidovna and XUSANOVA Diera Ziyadullaevna},
  journal = {Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali},
  year = {2025},
  volume = {10},
  number = {3/1},
  url = {https://tadqiqot.uz/index.php/biomedicine/article/view/12046}
}

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