Analysis of cytokine profile in gingival crevicular fluid of patients with aggressive periodontitis: pathogenetic and diagnostic aspects

RIZAEV Jasur Alimjanovich, GAIBULLAEv Elbek Azizbekovich, AKRAMOVA Nozima Akramovna, PUSTOVETOVA Maria Genadievna

Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali · 2025-yil

Annotatsiya

Aggressive periodontitis (AP) is a severe form of periodontal disease characterized by rapid tissue loss and significant inflammatory response. Immune mechanisms play a crucial role in the pathogenesis of AP, particularly through the activity of cytokines — mediators of inflammation that regulate the immune response and influence the progression of the disease. Studying the cytokine profile provides a deeper understanding of the pathogenesis of AP and aids in developing effective approaches for its diagnosis and treatment. This study aimed to investigate the levels of cytokines IL-1β, IL-4, and TNF-α in the gingival crevicular fluid of patients with different forms of AP.

Maqola ma’lumotlari
MualliflarRIZAEV Jasur Alimjanovich, GAIBULLAEv Elbek Azizbekovich, AKRAMOVA Nozima Akramovna, PUSTOVETOVA Maria Genadievna
JurnalJournal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali
NashriyotТошкент давлат стоматалогия институти, , «Expert Lawyers» MЧЖ
ISSN2181-9300
Nashr sanasi2025-03-27
Jild10
Son1
TilIngliz
Ilmiy sohaTibbiyot
Indeksga qo‘shilgan2026-09-13

Maqolaning asl sahifasi

Kalit so‘zlar

Агрессивный пародонтит, профиль цитокинов, жидкость десневой борозды, медиаторы воспаления, Aggressive periodontitis, cytokine profile, gingival crevicular fluid, inflammation mediators

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Iqtibos keltirish

APARIZAEV Jasur Alimjanovich, GAIBULLAEv Elbek Azizbekovich, AKRAMOVA Nozima Akramovna, & PUSTOVETOVA Maria Genadievna (2025). ANALYSIS OF CYTOKINE PROFILE IN GINGIVAL CREVICULAR FLUID OF PATIENTS WITH AGGRESSIVE PERIODONTITIS: PATHOGENETIC AND DIAGNOSTIC ASPECTS. Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 10(1). https://tadqiqot.uz/index.php/biomedicine/article/view/11157
GOST (OAK)RIZAEV Jasur Alimjanovich va b. ANALYSIS OF CYTOKINE PROFILE IN GINGIVAL CREVICULAR FLUID OF PATIENTS WITH AGGRESSIVE PERIODONTITIS: PATHOGENETIC AND DIAGNOSTIC ASPECTS // Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali. – 2025. – T. 10, № 1.
MLARIZAEV Jasur Alimjanovich, GAIBULLAEv Elbek Azizbekovich, AKRAMOVA Nozima Akramovna, and PUSTOVETOVA Maria Genadievna. “ANALYSIS OF CYTOKINE PROFILE IN GINGIVAL CREVICULAR FLUID OF PATIENTS WITH AGGRESSIVE PERIODONTITIS: PATHOGENETIC AND DIAGNOSTIC ASPECTS.” Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 10(1), 2025. https://tadqiqot.uz/index.php/biomedicine/article/view/11157
ChicagoRIZAEV Jasur Alimjanovich, GAIBULLAEv Elbek Azizbekovich, AKRAMOVA Nozima Akramovna, and PUSTOVETOVA Maria Genadievna. “ANALYSIS OF CYTOKINE PROFILE IN GINGIVAL CREVICULAR FLUID OF PATIENTS WITH AGGRESSIVE PERIODONTITIS: PATHOGENETIC AND DIAGNOSTIC ASPECTS.” Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 10(1) (2025). https://tadqiqot.uz/index.php/biomedicine/article/view/11157
HarvardRIZAEV Jasur Alimjanovich, GAIBULLAEv Elbek Azizbekovich, AKRAMOVA Nozima Akramovna, and PUSTOVETOVA Maria Genadievna (2025) ‘ANALYSIS OF CYTOKINE PROFILE IN GINGIVAL CREVICULAR FLUID OF PATIENTS WITH AGGRESSIVE PERIODONTITIS: PATHOGENETIC AND DIAGNOSTIC ASPECTS’, Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 10(1). https://tadqiqot.uz/index.php/biomedicine/article/view/11157
BibTeX
@article{rizaevjasuralimjanovich2025,
  title = {ANALYSIS OF CYTOKINE PROFILE IN GINGIVAL CREVICULAR FLUID OF PATIENTS WITH AGGRESSIVE PERIODONTITIS: PATHOGENETIC AND DIAGNOSTIC ASPECTS},
  author = {RIZAEV Jasur Alimjanovich and GAIBULLAEv Elbek Azizbekovich and AKRAMOVA Nozima Akramovna and PUSTOVETOVA Maria Genadievna},
  journal = {Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali},
  year = {2025},
  volume = {10},
  number = {1},
  url = {https://tadqiqot.uz/index.php/biomedicine/article/view/11157}
}

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