The role of vascular endothelial growth factor (vegf) in ovarian cancer with peritoneal carcinomatosis in stages III and IV

ULMASOV Firdavs Gayratovich, ESANKULOVA Bustonoy Sobirovna

Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali · 2025-yil

Annotatsiya

Ovarian cancer, particularly in advanced stages III and IV with peritoneal carcinomatosis (PC), presents significant challenges in treatment and prognosis. Vascular endothelial growth factor (VEGF) has been identified as a key regulator of tumor angiogenesis, facilitating tumor progression, metastasis, and resistance to therapy. This study aimed to evaluate the concentration of VEGF in plasma and peritoneal effusion in patients with ovarian cancer and to explore its prognostic significance. A total of 35 patients undergoing cytoreductive surgery were analyzed, and VEGF levels were assessed using enzyme-linked immunosorbent assay (ELISA). Additionally, high VEGF expression was found to be associated with poor prognosis, reduced progression-free survival, and overall survival in stage IV patients. These findings underscore the importance of VEGF as a potential prognostic biomarker and therapeutic target in ovarian cancer with peritoneal carcinomatosis. Further research is warranted to explore targeted anti-VEGF strategies to improve patient outcomes.

Maqola ma’lumotlari
MualliflarULMASOV Firdavs Gayratovich, ESANKULOVA Bustonoy Sobirovna
JurnalJournal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali
NashriyotТошкент давлат стоматалогия институти, , «Expert Lawyers» MЧЖ
ISSN2181-9300
Nashr sanasi2025-03-26
Jild10
Son1
TilIngliz
Ilmiy sohaTibbiyot
Indeksga qo‘shilgan2026-09-13

Maqolaning asl sahifasi

Kalit so‘zlar

Рак яичников, перитонеальный карциноматоз, сосудистый эндотелиальный фактор роста (VEGF), ангиогенез опухоли, биомаркер, прогноз, Ovarian cancer, peritoneal carcinomatosis, vascular endothelial growth factor (VEGF), tumor angiogenesis, biomarker, prognosis, tuxumdon saratoni, peritoneal kartsinomatoz, tomir endotelial o‘sish omili (VEGF), o‘sma angiogenezi, biomarker, prognoz

Ilmiy soha

Tibbiyot

Iqtibos keltirish

APAULMASOV Firdavs Gayratovich, & ESANKULOVA Bustonoy Sobirovna (2025). THE ROLE OF VASCULAR ENDOTHELIAL GROWTH FACTOR (VEGF) IN OVARIAN CANCER WITH PERITONEAL CARCINOMATOSIS IN STAGES III AND IV. Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 10(1). https://tadqiqot.uz/index.php/biomedicine/article/view/11154
GOST (OAK)ULMASOV Firdavs Gayratovich, ESANKULOVA Bustonoy Sobirovna THE ROLE OF VASCULAR ENDOTHELIAL GROWTH FACTOR (VEGF) IN OVARIAN CANCER WITH PERITONEAL CARCINOMATOSIS IN STAGES III AND IV // Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali. – 2025. – T. 10, № 1.
MLAULMASOV Firdavs Gayratovich, and ESANKULOVA Bustonoy Sobirovna. “THE ROLE OF VASCULAR ENDOTHELIAL GROWTH FACTOR (VEGF) IN OVARIAN CANCER WITH PERITONEAL CARCINOMATOSIS IN STAGES III AND IV.” Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 10(1), 2025. https://tadqiqot.uz/index.php/biomedicine/article/view/11154
ChicagoULMASOV Firdavs Gayratovich, and ESANKULOVA Bustonoy Sobirovna. “THE ROLE OF VASCULAR ENDOTHELIAL GROWTH FACTOR (VEGF) IN OVARIAN CANCER WITH PERITONEAL CARCINOMATOSIS IN STAGES III AND IV.” Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 10(1) (2025). https://tadqiqot.uz/index.php/biomedicine/article/view/11154
HarvardULMASOV Firdavs Gayratovich, and ESANKULOVA Bustonoy Sobirovna (2025) ‘THE ROLE OF VASCULAR ENDOTHELIAL GROWTH FACTOR (VEGF) IN OVARIAN CANCER WITH PERITONEAL CARCINOMATOSIS IN STAGES III AND IV’, Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 10(1). https://tadqiqot.uz/index.php/biomedicine/article/view/11154
BibTeX
@article{ulmasovfirdavsgayratovich2025,
  title = {THE ROLE OF VASCULAR ENDOTHELIAL GROWTH FACTOR (VEGF) IN OVARIAN CANCER WITH PERITONEAL CARCINOMATOSIS IN STAGES III AND IV},
  author = {ULMASOV Firdavs Gayratovich and ESANKULOVA Bustonoy Sobirovna},
  journal = {Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali},
  year = {2025},
  volume = {10},
  number = {1},
  url = {https://tadqiqot.uz/index.php/biomedicine/article/view/11154}
}

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