The problem of the side effects of antiretroviral drugs in HIV infection

Z.I., Axmedjanova, D.M., Urunova, D.A., Karimov, З.И , Ахмеджанова, Д.М, Урунова, Д.А., Каримов, З.И., Ахмеджанова, Д.М, Урунова, Д.А. , Каримов

Жамият ва инновациялар / Общество и инновации / Society and innovations · 2020-yil

Annotatsiya

The article is devoted to the problems of the development of Currently used antiretroviral therapy has made HIV infection a chronic controlled infection and has prolonged life and quality of life. However, any antiretroviral drug has side effects, although not on every patient and not always the same. To assess the current state of the side effects problem of antiretroviral therapy in HIV - infected patients based on the analysis of literature data. The following are data on the side effects of various groups of antiretroviral drugs used in the past and now, as well as some of their representatives. Antiretroviral drugs exhibit various side effects, in particular mitochondrial toxicity caused by nucleoside reverse transcriptase inhibitors (NRTIs), causing a wide range of side effects such as lactic acidosis, hepatic steatosis, myopathy, cardiomyopathy, peripheral neuropathy, pancreatitis, and possibly lipodystrophy syndrome. In general, integrase inhibitors are well tolerated and cause minimal drug interactions The use of older antiretroviral drugs has been associated with a variety of side effects, which include lactic acidosis, hepatic steatosis, allergic reactions, myopathy, cardiomyopathy, peripheral neuropathy, pancreatitis and lipoatrophy.These side effects are less common with newer recommended ARVs. drugs. When treating, it is necessary to consider the likelihood of side effects and the possibility of their prevention.

Maqola ma’lumotlari
MualliflarZ.I., Axmedjanova, D.M., Urunova, D.A., Karimov, З.И , Ахмеджанова, Д.М, Урунова, Д.А., Каримов, З.И., Ахмеджанова, Д.М, Урунова, Д.А. , Каримов
JurnalЖамият ва инновациялар / Общество и инновации / Society and innovations
Nashr sanasi2020-11-18
Jild1
Son1/s
Betlar604-617
TilRus
DOI10.47689/2181-1415-vol1-iss1/s-pp604-617

Kalit so‘zlar

ВИЧ-инфекция антиретровирусные, препараты, Побочные эффекты АРВТ, HIV-infection, Antiretroviral preparations, By-effects antiretroviral therapy, ОИВ инфекциясида антиретровируслари, Препаратлар, Ножуя таъсирларининг муаммолари

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