Objective: Investigation of morphofunctional changes in the stomach wall in white rats aged 36 weeks exposed to energy drinks using laboratory research methods. Methods: Healthy white male rats participated in the study. The experimental rats were divided into two groups. Morphofunctional changes in the stomach wall caused by the consumption of energy drinks in rat blood samples were evaluated using the enzyme immunoassay (ELISA). Blood samples taken for enzyme immunoassay were centrifuged and immunological tests were performed for pepsenogen 1 (pg1) and pepsenogen 2 (PG2), the cancer marker SA74-2 in serum samples. Results: According to the analysis of the data obtained, it was found that the degree of severity of morphofunctional changes in the stomach wall in experimental animals of the main group depends precisely on the duration of action of the energy drink. A decrease in the ratio of PG1, PG2 in the blood and PG1/PG2 was observed to a lesser extent as a result of drinking an energy drink for 4 weeks. However, in the case of experimental rats who constantly (12 weeks) consumed an energy drink, it was found that the amount of PG1, PG2 decreased significantly. During the experiment, it was found that the specific serum antigen CA 74-2 increased by 23.5 times and a sharp decrease in the level of pepsinogen 1,2 and the ratio PG1/PG2, indicating the morphofunctional state of the stomach wall when taken for a long period of time, indicates damage to the glands of the stomach floor. The fact that the concentration of cancer markers CA 74-2 is sharply increased indicates the occurrence of metaplasia of glandular epithelial cells of the stomach wall. Summary. Thus, the experiment showed that the level of changes in the morphofunctional state of the stomach wall in rats precisely depends on the duration of consumption of an energy drink. In 9-month-old rats who chronically consumed an energy drink, the level of PG1 increased by 79% and PG2 by 62%, the ratio of PG1/PG2 decreased by 46%, and the content of CA 74-2 increased by 23.5 times. The information provided indicates the appearance of symptoms of atrophy of the mucous membrane of the stomach wall
| Mualliflar | YUSUPOVA Nargiza Abdikodirovna, ORIPOV Firdavs Sur'atovich |
|---|---|
| Jurnal | Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali |
| Nashriyot | Тошкент давлат стоматалогия институти, , «Expert Lawyers» MЧЖ |
| ISSN | 2181-9300 |
| Nashr sanasi | 2024-12-25 |
| Jild | 9 |
| Son | 5 |
| Til | Ingliz |
| Ilmiy soha | Tibbiyot |
| Indeksga qo‘shilgan | 2026-08-27 |
иммуноферментный анализ, пепсиноген 1, пепсиноген 2, энергетический напиток, сыворотка крови, крыса, желудок, enzyme immunoassay, pepsinogen 1, pepsinogen 2, energy drink, blood serum, rat, stomach, immunoferment tahlil, pepsinogen 1, pepsinogen 2, energetik ichimlik, qon zardobi, kalamush, oshqozon
| APA | YUSUPOVA Nargiza Abdikodirovna, & ORIPOV Firdavs Sur'atovich (2024). MORPHOFUNCTIONAL CHANGES IN THE STOMACH WALL CAUSED BY ENERGY DRINKS. Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 9(5). https://tadqiqot.uz/index.php/biomedicine/article/view/10634 |
|---|---|
| GOST (OAK) | YUSUPOVA Nargiza Abdikodirovna, ORIPOV Firdavs Sur'atovich MORPHOFUNCTIONAL CHANGES IN THE STOMACH WALL CAUSED BY ENERGY DRINKS // Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali. – 2024. – T. 9, № 5. |
| MLA | YUSUPOVA Nargiza Abdikodirovna, and ORIPOV Firdavs Sur'atovich. “MORPHOFUNCTIONAL CHANGES IN THE STOMACH WALL CAUSED BY ENERGY DRINKS.” Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 9(5), 2024. https://tadqiqot.uz/index.php/biomedicine/article/view/10634 |
| Chicago | YUSUPOVA Nargiza Abdikodirovna, and ORIPOV Firdavs Sur'atovich. “MORPHOFUNCTIONAL CHANGES IN THE STOMACH WALL CAUSED BY ENERGY DRINKS.” Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 9(5) (2024). https://tadqiqot.uz/index.php/biomedicine/article/view/10634 |
| Harvard | YUSUPOVA Nargiza Abdikodirovna, and ORIPOV Firdavs Sur'atovich (2024) ‘MORPHOFUNCTIONAL CHANGES IN THE STOMACH WALL CAUSED BY ENERGY DRINKS’, Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 9(5). https://tadqiqot.uz/index.php/biomedicine/article/view/10634 |
| BibTeX | @article{yusupovanargizaabdikodirovna2024,
title = {MORPHOFUNCTIONAL CHANGES IN THE STOMACH WALL CAUSED BY ENERGY DRINKS},
author = {YUSUPOVA Nargiza Abdikodirovna and ORIPOV Firdavs Sur'atovich},
journal = {Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali},
year = {2024},
volume = {9},
number = {5},
url = {https://tadqiqot.uz/index.php/biomedicine/article/view/10634}
} |
Boshqa maqola uchun iqtibos tayyorlash
Benign gallbladder diseases typically present with intraluminal lesions and localized or diffuse wall thickening. Intraluminal lesions of the gallbladder include gallstones, cholesterol polyps, adenomas, or biliary…
S100 proteins are small calcium-binding molecules with a specific EF-hand structure. These proteins are found throughout vertebrate bodies and serve many vital functions. Different cell types contain specific sets of…
The study of the chronic toxicity of the drug Colchiprit-neo in rats with oral administration at doses of 30.0, 61.0 and 120 mg/kg for 30 days was carried out. It has been shown that with repeated oral administration to…
Malignant epithelial ovarian tumors account for 90% of all cases, with serous carcinomas accounting for up to 85%. Due to high molecular and genetic heterogeneity, as well as resistance to chemotherapy, it is difficult…
Primary tumors of the central nervous system unite tumors that differ in histological structure, malignancy and clinical course, common to them is their origin from the tissues that make up the central nervous system…
Aim: to study experimentally the insulin-producing function of the pancreas, lipid peroxidation indices and the antioxidant defense system in rats exposed to lead. Materials and methods: The experiment was conducted on…
The article describes the features of innervation and adrenergic nerve fibers of the extrahepatic bile ducts in rabbits. After experimental cholecystectomy, reactive changes in nerve fibers were observed in the wall of…
Bladder cancer most of these tumors are represented by urothelial cancer and can be characterized by varying degrees of differentiation and invasiveness. In many cases, Bladder cancer develops against the background of…
Purpose of the study. Conducting a literary analysis taking into account the morphological and radiological features of the development of pneumonia. Conclusion. Literary data show that to improve and timely diagnosis…
Experimental studies have shown that energy drink consumption is a powerful source of liver enzyme disruption. Significant increases in liver enzymes have been observed, which are sufficient to cause signs and symptoms…
Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali — barcha maqolalar · 2024-yil arxivi
Inflammatory diseases of the skeleton are one of the most severe and common diseases of the musculoskeletal system in children and adolescents, including a large group of destructive bone lesions of various etiologies…
The results of studies, the criteria for the normal composition ofb the vaginal microbiocenosis (Volume of secretcions their acidity, quantitative and qualitative composition of microflora) and regulatory mechanisms…
In recent years, in a number of countries, when screening for various diseases of the stomach, including peptic ulcer of the stomach and duodenum, gastroesophageal reflux, atrophic gastritis and other diseases of the…
Objective: Evaluation of clinical and laboratory parameters in patients with urolithiasis and analysis of the quality of laboratory care at the stationary stage. Methods: The appealability was studied at the 2nd clinic…
Objective: Evaluation of functional changes in the stomach under the influence of energy drinks by laboratory methods Methods: The experiment was performed on 30 three-month-old white male rats weighing 130 ± 20 g. To…
Objective: Evaluation of functional changes in the stomach under the influence of energy drinks and the results of their correction with sesame oil Methods: The experiment was carried out on 43 three-month-old white…
Настоящее исследование посвящено разработке алгоритма раннего выявления сенсоневральной тугоухости у детей с использованием методов полимеразной цепной реакции (ПЦР). Обследовано 235 детей с нарушениями слуха, из…
В статье представлены клинические аспекты и диагностические проблемы выявления сенсоневральной тугоухости у новорождённых с перинатальной патологией. Обследовано 115 новорождённых, из которых 35 перенесли асфиксию, а у…
Сенсоневральная тугоухость (СНТ) у детей остаётся одной из наиболее актуальных проблем современной оториноларингологии и медицинской генетики. Ранняя диагностика нарушений слуха играет ключевую роль в предупреждении…
Сенсоневральная тугоухость у новорождённых является одной из ведущих причин нарушения слухоречевого развития и ранней инвалидизации. Наиболее уязвимыми считаются дети, перенёсшие перинатальные осложнения, такие как…
Mazkur eksperimental tadqiqotda yuqori yog‘li ratsion va seftriaksonning lipid hamda uglevod almashinuviga alohida va birgalikdagi ta’siri 160 ta oq zotsiz erkak kalamushda o‘rganildi. Tajriba hayvonlari to‘rtta guruhga…
Мазкур тадқиқотда Тошкет вилоятидаги Ўрта Чирчиқ тумани 25-сонли, Бўка тумани 3-сонли ва 9-сонли давлат мактабгача таълим ташкилотларида 2025 йил ёз мавсумидаги таомномаларнинг озиқ-овқат маҳсулотлари билан…