STUDY OF THE TOXICOLOGY OF THE ANTITUMOR DRUG Colchiprit-neo (K-20)

UROZOV Nuriddin Elmurotovich, VYPOVA Natalia Leonidovna, NISHANOV Danier Anarbaevich, MADALIEV Akhror Alievich, IBRAGIMOV Shavkat Narzikulovich, ENIKEEVA Zulfiya Makhmudovna

Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali · 2024-yil

Annotatsiya

The study of the chronic toxicity of the drug Colchiprit-neo in rats with oral administration at doses of 30.0, 61.0 and 120 mg/kg for 30 days was carried out. It has been shown that with repeated oral administration to rats, the drug does not affect the behavior and weight dynamics of animals, does not have a toxic effect on the composition of peripheral blood, kidney function, but increases AlAt in the liver, however, after 1 month of the recovery period, all these indicators changed within the physiological norm. A pathomorphological study of the internal organs of rats showed that when applying a dose of 30 mg / kg, toxicity does not manifest itself when affecting the internal parenchymal organs. All the above data allow us to conclude that the drug in a therapeutic dose does not have a toxic effect on the animal body.

Maqola ma’lumotlari
MualliflarUROZOV Nuriddin Elmurotovich, VYPOVA Natalia Leonidovna, NISHANOV Danier Anarbaevich, MADALIEV Akhror Alievich, IBRAGIMOV Shavkat Narzikulovich, ENIKEEVA Zulfiya Makhmudovna
JurnalJournal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali
NashriyotТошкент давлат стоматалогия институти, , «Expert Lawyers» MЧЖ
ISSN2181-9300
Nashr sanasi2024-12-25
Jild9
Son5
TilIngliz
Ilmiy sohaTibbiyot
Indeksga qo‘shilgan2026-08-27

Maqolaning asl sahifasi

Kalit so‘zlar

препарат Колхиприт-нео», пероральное введение, хроническая токсичность, Colchiprit-neo drug, oral administration, chronic toxicity

Ilmiy soha

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Iqtibos keltirish

APAUROZOV Nuriddin Elmurotovich, VYPOVA Natalia Leonidovna, NISHANOV Danier Anarbaevich, MADALIEV Akhror Alievich, IBRAGIMOV Shavkat Narzikulovich, & ENIKEEVA Zulfiya Makhmudovna (2024). STUDY OF THE TOXICOLOGY OF THE ANTITUMOR DRUG Colchiprit-neo (K-20). Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 9(5). https://tadqiqot.uz/index.php/biomedicine/article/view/10631
GOST (OAK)UROZOV Nuriddin Elmurotovich va b. STUDY OF THE TOXICOLOGY OF THE ANTITUMOR DRUG Colchiprit-neo (K-20) // Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali. – 2024. – T. 9, № 5.
MLAUROZOV Nuriddin Elmurotovich, VYPOVA Natalia Leonidovna, NISHANOV Danier Anarbaevich, MADALIEV Akhror Alievich, IBRAGIMOV Shavkat Narzikulovich, and ENIKEEVA Zulfiya Makhmudovna. “STUDY OF THE TOXICOLOGY OF THE ANTITUMOR DRUG Colchiprit-neo (K-20).” Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 9(5), 2024. https://tadqiqot.uz/index.php/biomedicine/article/view/10631
ChicagoUROZOV Nuriddin Elmurotovich, VYPOVA Natalia Leonidovna, NISHANOV Danier Anarbaevich, MADALIEV Akhror Alievich, IBRAGIMOV Shavkat Narzikulovich, and ENIKEEVA Zulfiya Makhmudovna. “STUDY OF THE TOXICOLOGY OF THE ANTITUMOR DRUG Colchiprit-neo (K-20).” Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 9(5) (2024). https://tadqiqot.uz/index.php/biomedicine/article/view/10631
HarvardUROZOV Nuriddin Elmurotovich, VYPOVA Natalia Leonidovna, NISHANOV Danier Anarbaevich, MADALIEV Akhror Alievich, IBRAGIMOV Shavkat Narzikulovich, and ENIKEEVA Zulfiya Makhmudovna (2024) ‘STUDY OF THE TOXICOLOGY OF THE ANTITUMOR DRUG Colchiprit-neo (K-20)’, Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 9(5). https://tadqiqot.uz/index.php/biomedicine/article/view/10631
BibTeX
@article{urozovnuriddinelmurotovich2024,
  title = {STUDY OF THE TOXICOLOGY OF THE ANTITUMOR DRUG Colchiprit-neo (K-20)},
  author = {UROZOV Nuriddin Elmurotovich and VYPOVA Natalia Leonidovna and NISHANOV Danier Anarbaevich and MADALIEV Akhror Alievich and IBRAGIMOV Shavkat Narzikulovich and ENIKEEVA Zulfiya Makhmudovna},
  journal = {Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali},
  year = {2024},
  volume = {9},
  number = {5},
  url = {https://tadqiqot.uz/index.php/biomedicine/article/view/10631}
}

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