Objective: Improving the results of treatment of steroid-dependent and steroid-resistant forms of ulcerative colitis. Methods: The study is based on the results of treatment of 105 patients with nonspecific ulcerative colitis with hormone-resistant and hormone-dependent forms, admitted to the surgical departments of the multidisciplinary clinic of Samarkand State Medical University in the period from 2012 to 2021. Results: In patients of the main group on the background of plasmapheresis, we received a complete response in 30 (64%) of 47 patients, an incomplete response in 15 (32%) patients, a partial response in 2 (4%) patients. In patients of the control group, the results of treatment during these periods were significantly worse than in patients of the main group. Conclusions: The positive dynamics of general clinical, laboratory parameters and endoscopic picture in patients with steroid - dependent and steroid - resistant forms of ulcerative colitis when using for their treatment a course of plasmapheresis with indirect electrochemical detoxification of blood plasma with additional ozonation indicates its effectiveness in stopping the exacerbation of the disease.
| Mualliflar | ШОДМОНОВ Акбар Акрамович, KURBANIYAZOV Zafar Babajanovich, ASKAROV Pulat Azadovich |
|---|---|
| Jurnal | Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali |
| Nashr sanasi | 2023-11-01 |
| Jild | 8 |
| Son | 4 |
| Til | O‘zbek |
неспецифический язвенный колит, гормональная резистентность, гормональная зависимость, плазмаферез, ulcerative colitis, hormonal resistance, hormonal dependence, plasmapheresis, nospetsifik yarali kolit, gormonal qarshilik, gormonal qaramlik, plazmaferez
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