Systemic sclerosis is a progressive chronic autoimmune rheumatic disease with high morbidity and mortality. Systemic sclerosis a multi-organ disease that affects organs such as the skin, lungs, digestive system, heart, musculoskeletal system, kidneys, causing severe pain and disability, disability and death of patients. The main marker of an abnormal immune response is circulating autoantibodies, which are found in more than 95% of patients with systemic sclerosis. It is important to study the clinical, immunological, diagnostic and prognostic significance of autoantibodies, especially antifibrillary antibodies produced against the fibrillarin protein.
| Mualliflar | ZARIPOV Sanjarbek Istamovich, AKHMEDOV Khalmurad Sadullayevich, ABDURAKHMANOVA Nargiza Mirza-Bakhtiyarkhanovna |
|---|---|
| Jurnal | Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali |
| Nashr sanasi | 2023-05-26 |
| Jild | 8 |
| Son | 2 |
| Til | O‘zbek |
системная склеродермия, антинуклеарные антитела (АНА), фибрилларин, антифибриллярные антитела (АФА), феномен Рейно, модифицированная кожная шкала Роднана (mRSS), systemic sclerosis, antinuclear antibodies (ANA), fibrillarin, antifibrillary antibodies (AFA), Raynaud's phenomenon, modified Rodnan skin scale (mRSS), тизимли склеродермия, антинуклеар антитаналар (АНА), фибрилларин, антифибриллар антитаналар (АФА), Рейно феномени, модификацияланган Роднан тери шкаласи (mRSS)
The article analyzes the complications of surgical treatment of 216 primary patients with Hirschsprung's disease operated on by the Soave - Lenyushkin method, and the treatment of 54 patients admitted with various…
To study the quantitative indicators of cytokines in severe and moderate forms of hemolytic escherichiosis, a clinical and laboratory examination of 28 patients was carried out. The study included children aged 6 months…
In order to study clinical and statistical data, a prospective study of 63 infants with congenital intestinal obstruction was carried out. Depending on the types of intestinal obstruction, the children were divided into…
Objective: to study allergic reactions in children with congenital heart disease (CHD). Materials and Methods: The study included 103 children with septal congenital heart disease, who underwent clinical and anamnestic…
The treatment of pediatric urolithiasis is one of the most difficult tasks in urology. The introduction of new technological and advanced techniques has led to significant changes in the surgical treatment of…
Purpose of the study. Analysis of the role of the gene-determinant of the PGC-1A(G/A) inflammation regulator in the pathogenesis and course of gastric ulcer and duodenal ulcer. Materials and research methods. 100…
In order to identify the features of the immediate postoperative period, a prospective study was conducted in 30 children with reflux ureterohydronephrosis. The analysis was carried out depending on the correction of…
The activity of all organs is controlled by the nervous, endocrine and immune systems. The immune system also plays an important role in the activity of the nervous and endocrine systems. Over the past 10 years…
Currently, evaluation of the effectiveness of surgical treatment of malformations of the colon, in particular Hirschsprung's disease, is becoming increasingly important. According to various authors, approximately…
In the treatment of reactive arthritis, non-steroidal and steroidal anti-inflammatory drugs are used, depending on the degree of joint damage. In severe cases of chronic reactive arthritis, immunosuppressive therapy is…
Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali — barcha maqolalar