Antioxidant therapy and metobolic approaches to the treatment of chronic brucellosis.

ФАРМАНОВА Махтоб Алимовна

Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali · 2022-yil

Annotatsiya

Objective: To evaluate the effectiveness of phosphargine succinate in patients with chronic brucellosis. Materials and methods: The object of the study were 85 patients aged 17 to 74 years who were treated at the Bukhara Regional Infectious Diseases Hospital. Results and discussion: According to clinical forms, the patients were distributed as follows: primary chronic brucellosis (BCB) - 22 (25.8%) and secondary chronic brucellosis (ICB) - 63 (74.2%). Patients mainly complained of fever, weakness, headache, loss of appetite, tremor, sweating, and the like. But their meeting was different in primary and secondary chronic brucellosis. According to DAS28, it was 3.95±0.13 and 4.23±0.12 points in primary and secondary chronic brucellosis. We also evaluated LPO processes in the blood serum of patients with MDA levels. Based on the results obtained, we tried to improve the treatment of CB and for this we used the drug phosphargine succinate, produced in our republic. This drug has antihypoxant and antioxidant properties. Studies have shown it to be more effective than conventional treatment for chronic brucellosis. Conclusions: Chronic brucellosis is characterized by an increase in the amount of MDA, a weakening of the antioxidant defense system and a decrease in the compensatory capabilities of the antioxidant system, and their changes depend on the severity of the disease. The inclusion of the drug Phosfargin in the treatment of chronic brucellosis leads to early elimination of clinical symptoms.

Maqola ma’lumotlari
MualliflarФАРМАНОВА Махтоб Алимовна
JurnalJournal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali
NashriyotТошкент давлат стоматалогия институти, , «Expert Lawyers» MЧЖ
ISSN2181-9300
Nashr sanasi2022-12-11
Jild7
Son5
TilIngliz
Ilmiy sohaTibbiyot
Indeksga qo‘shilgan2026-08-27

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Kalit so‘zlar

Хронический бруцеллез, клиника, диагностика, антиоксидантная система, Chronic brucellosis, clinic, diagnosis, antioxidant system, Сурункали бруцеллёз, клиника, ташхисот, антиоксидант тизим

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Iqtibos keltirish

APAФАРМАНОВА Махтоб Алимовна (2022). ANTIOXIDANT THERAPY AND METOBOLIC APPROACHES TO THE TREATMENT OF CHRONIC BRUCELLOSIS.. Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 7(5). https://tadqiqot.uz/index.php/biomedicine/article/view/6057
GOST (OAK)ФАРМАНОВА Махтоб Алимовна ANTIOXIDANT THERAPY AND METOBOLIC APPROACHES TO THE TREATMENT OF CHRONIC BRUCELLOSIS. // Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali. – 2022. – T. 7, № 5.
MLAФАРМАНОВА Махтоб Алимовна. “ANTIOXIDANT THERAPY AND METOBOLIC APPROACHES TO THE TREATMENT OF CHRONIC BRUCELLOSIS..” Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 7(5), 2022. https://tadqiqot.uz/index.php/biomedicine/article/view/6057
ChicagoФАРМАНОВА Махтоб Алимовна. “ANTIOXIDANT THERAPY AND METOBOLIC APPROACHES TO THE TREATMENT OF CHRONIC BRUCELLOSIS..” Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 7(5) (2022). https://tadqiqot.uz/index.php/biomedicine/article/view/6057
HarvardФАРМАНОВА Махтоб Алимовна (2022) ‘ANTIOXIDANT THERAPY AND METOBOLIC APPROACHES TO THE TREATMENT OF CHRONIC BRUCELLOSIS.’, Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 7(5). https://tadqiqot.uz/index.php/biomedicine/article/view/6057
BibTeX
@article{article2022,
  title = {ANTIOXIDANT THERAPY AND METOBOLIC APPROACHES TO THE TREATMENT OF CHRONIC BRUCELLOSIS.},
  author = {ФАРМАНОВА Махтоб Алимовна},
  journal = {Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali},
  year = {2022},
  volume = {7},
  number = {5},
  url = {https://tadqiqot.uz/index.php/biomedicine/article/view/6057}
}

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