DIMETALATION OF BIS-CARBAMATE MEE-1 AND IN SILICO STUDY OF PHYSICOCHEMICAL PARAMETERS

Mashaev, Eldor, Pulatov, Khayrulla, Yuldashev, Alisher

Innovations in Science and Technologies · 2024-yil

Annotatsiya

This scientific work is devoted to the dimetalation of N,N'-hexamethylene bis-[(ortho-cresolyl)-carbamate] and the synthesis of N,N'- disodium, N,N'-hexamethylene bis-[(ortho-cresolyl)-carbamate] i.e. MEE-1b. As a result, distrium substituted bis-carbamate MEE-1b was obtained in high yield. In silico primary screenings were carried out to study the elemental composition, some physicochemical properties and biological activities. As a result, it was revealed that bis-carbamate MEE-1b can be used as an inhibitor and substrate of cytochrome. And also in the treatment of phobic disorders. Further study in real in vitro and in vivo analyzes is also recommended.

Maqola ma’lumotlari
MualliflarMashaev, Eldor, Pulatov, Khayrulla, Yuldashev, Alisher
JurnalInnovations in Science and Technologies
Nashr sanasi2024-03-24
Jild1
Son1
Betlar28-36
TilIngliz

Kalit so‘zlar

Bis-carbamate, pass online, screening, sodium, activity, inhibitor, substrate, phobic, cytochrome.

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