Multimodal approach to diagnosing polyneuropathies of various origins in children

Gulomov, Kakhkhorali, Гуломов, Каххорали, G‘ulomov, Qaxxorali

Халқаро илмий педиатрия журнали · 2025-yil

Annotatsiya

Background: Polyneuropathies in children pose diagnostic challenges due to their diverse etiologies, age-specific clinical presentations, and the need for specialized assessment techniques. A multimodal diagnostic approach, combining clinical evaluation, electrophysiology, laboratory studies, and imaging, is crucial for accurate diagnosis and management. Objective: To evaluate the effectiveness of a structured multimodal diagnostic approach in identifying pediatric polyneuropathies and determine the diagnostic yield of various modalities. Methods: A retrospective analysis was conducted on 85 pediatric patients (age range: 0-18 years) suspected of having polyneuropathy at Fergana Regional Children’s Multidisciplinary Medical Center. The diagnostic protocol included comprehensive clinical assessment, nerve conduction studies (NCS) and electromyography (EMG), targeted laboratory investigations, neuroimaging, and genetic testing when indicated. Results: Definitive diagnoses were established in 78 patients (91.8%). The most common etiologies were hereditary neuropathies (34.1%), immune-mediated inflammatory neuropathies (28.2%), and metabolic causes (15.3%). Nerve conduction studies had the highest diagnostic yield (89.4%), followed by targeted genetic testing (72.3% in hereditary cases) and laboratory investigations (68.2%). Conclusions: A structured multimodal approach significantly improves diagnostic accuracy in pediatric polyneuropathies. Early use of electrophysiological studies, combined with targeted laboratory and genetic testing, enables timely diagnosis and appropriate intervention.

Maqola ma’lumotlari
MualliflarGulomov, Kakhkhorali, Гуломов, Каххорали, G‘ulomov, Qaxxorali
JurnalХалқаро илмий педиатрия журнали
NashriyotАндижон давлат тиббиёт институти; In Science МЧЖ
ISSN2181-2926, 2181-2926
Nashr sanasi2025-11-04
Jild4
Son5
Betlar1078-1083
TilIngliz
Ilmiy sohaTibbiyot
DOI10.56121/2181-2926-2025-4-5-1078-1083
Indeksga qo‘shilgan2026-08-26

DOI: 10.56121/2181-2926-2025-4-5-1078-1083 · Maqolaning asl sahifasi

Kalit so‘zlar

полинейропатия, детская неврология, мультимодальная диагностика, исследования проводимости нервов, электромиография, дети, polyneuropathy, pediatric neurology, multimodal diagnosis, nerve conduction studies, electromyography, children, polinevropatiya, bolalar nevrologiyasi, ko‘p usullik tashxislash, asab o‘tkazuvchanligi tadqiqotlari, elektromiografiya, bolalar

Ilmiy soha

Tibbiyot

Iqtibos keltirish

APAGulomov, Kakhkhorali, Гуломов, Каххорали, & G‘ulomov, Qaxxorali (2025). MULTIMODAL APPROACH TO DIAGNOSING POLYNEUROPATHIES OF VARIOUS ORIGINS IN CHILDREN. Халқаро илмий педиатрия журнали, 4(5), 1078-1083. https://doi.org/10.56121/2181-2926-2025-4-5-1078-1083
GOST (OAK)Gulomov, Kakhkhorali, Гуломов, Каххорали, G‘ulomov, Qaxxorali MULTIMODAL APPROACH TO DIAGNOSING POLYNEUROPATHIES OF VARIOUS ORIGINS IN CHILDREN // Халқаро илмий педиатрия журнали. – 2025. – T. 4, № 5. – P. 1078-1083. – DOI: 10.56121/2181-2926-2025-4-5-1078-1083.
MLAGulomov, Kakhkhorali, Гуломов, Каххорали, and G‘ulomov, Qaxxorali. “MULTIMODAL APPROACH TO DIAGNOSING POLYNEUROPATHIES OF VARIOUS ORIGINS IN CHILDREN.” Халқаро илмий педиатрия журнали, 4(5), 1078-1083, 2025. https://doi.org/10.56121/2181-2926-2025-4-5-1078-1083
ChicagoGulomov, Kakhkhorali, Гуломов, Каххорали, and G‘ulomov, Qaxxorali. “MULTIMODAL APPROACH TO DIAGNOSING POLYNEUROPATHIES OF VARIOUS ORIGINS IN CHILDREN.” Халқаро илмий педиатрия журнали, 4(5), 1078-1083 (2025). https://doi.org/10.56121/2181-2926-2025-4-5-1078-1083
HarvardGulomov, Kakhkhorali, Гуломов, Каххорали, and G‘ulomov, Qaxxorali (2025) ‘MULTIMODAL APPROACH TO DIAGNOSING POLYNEUROPATHIES OF VARIOUS ORIGINS IN CHILDREN’, Халқаро илмий педиатрия журнали, 4(5), 1078-1083. https://doi.org/10.56121/2181-2926-2025-4-5-1078-1083
BibTeX
@article{gulomovkakhkhorali2025,
  title = {MULTIMODAL APPROACH TO DIAGNOSING POLYNEUROPATHIES OF VARIOUS ORIGINS IN CHILDREN},
  author = {Gulomov, Kakhkhorali and Гуломов, Каххорали and G‘ulomov, Qaxxorali},
  journal = {Халқаро илмий педиатрия журнали},
  year = {2025},
  volume = {4},
  number = {5},
  pages = {1078-1083},
  doi = {10.56121/2181-2926-2025-4-5-1078-1083},
  url = {https://doi.org/10.56121/2181-2926-2025-4-5-1078-1083}
}

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