Clinical-laboratory characteristics of enteroviral meningitis without pleocytosis in children

Abdukadirova, Nargiza, Абдукадирова, Наргиза, Abdukadirova, Nargiza

Халқаро илмий педиатрия журнали · 2025-yil

Annotatsiya

Objective. To identify clinical and laboratory features of enteroviral meningitis without pleocytosis in children depending on the presence of cerebrospinal fluid pleocytosis in the Samarkand region. Materials and methods. A retrospective study was conducted of patients under the age of 18 who sought treatment at the Samarkand Infectious Diseases Hospital from May 2016 to May 2023. The patients were divided into 2 groups: 1-group consisted of 7 patients with enteroviral meningitis with pleocytosis in the cerebrospinal fluid, and 2-group consisted of 10 patients without pleocytosis. A quantitative real-time thermal block Exicycler 96 was used for reverse transcription polymerase chain reaction (RT-PCR). Results. All children in both groups complained of headaches. Hyperthermia was complained of by 6 (85.7%) children in 1 group and 8 (80%) children in 2 group. Vomiting was observed in 3 children (42.9%) in 1group and in 4 children (40.0%) in 2 group. Signs of meningeal irritation were positive in all patients in the pleocytosis group and in 8 (80%) patients in the non-pleocytosis group. All patients in the pleocytosis group were hospitalized, and nine (90%) patients in the non-pleocytosis group were refused hospitalization. The peripheral leukocyte counts as well as the mean C-reactive protein level were significantly higher in the pleocytosis group than in the non-pleocytosis group. The median cerebrospinal fluid pressure was higher in the non-pleocytosis group than in the pleocytosis group. Conclusion. Children with meningitis symptoms during an enterovirus epidemic and high cerebrospinal fluid pressure and protein levels should undergo RT-PCR to verify the diagnosis, even if the cerebrospinal fluid leukocyte count is normal.

Maqola ma’lumotlari
MualliflarAbdukadirova, Nargiza, Абдукадирова, Наргиза, Abdukadirova, Nargiza
JurnalХалқаро илмий педиатрия журнали
NashriyotАндижон давлат тиббиёт институти; In Science МЧЖ
ISSN2181-2926, 2181-2926
Nashr sanasi2025-04-18
Jild4
Son2
Betlar928-934
TilIngliz
Ilmiy sohaTibbiyot
DOI10.56121/2181-2926-2025-4-2-928-934
Indeksga qo‘shilgan2026-08-26

DOI: 10.56121/2181-2926-2025-4-2-928-934 · Maqolaning asl sahifasi

Kalit so‘zlar

энтеровирусный менингит, дети, плеоцитоз, спинномозговая жидкость, enterovirus meningitis, children, pleocytosis, cerebrospinal fluid, enterovirus meningit, bolalar, pleotsitoz, miya omurilik suyuqligi

Ilmiy soha

Tibbiyot

Iqtibos keltirish

APAAbdukadirova, Nargiza, Абдукадирова, Наргиза, & Abdukadirova, Nargiza (2025). CLINICAL-LABORATORY CHARACTERISTICS OF ENTEROVIRAL MENINGITIS WITHOUT PLEOCYTOSIS IN CHILDREN. Халқаро илмий педиатрия журнали, 4(2), 928-934. https://doi.org/10.56121/2181-2926-2025-4-2-928-934
GOST (OAK)Abdukadirova, Nargiza, Абдукадирова, Наргиза, Abdukadirova, Nargiza CLINICAL-LABORATORY CHARACTERISTICS OF ENTEROVIRAL MENINGITIS WITHOUT PLEOCYTOSIS IN CHILDREN // Халқаро илмий педиатрия журнали. – 2025. – T. 4, № 2. – P. 928-934. – DOI: 10.56121/2181-2926-2025-4-2-928-934.
MLAAbdukadirova, Nargiza, Абдукадирова, Наргиза, and Abdukadirova, Nargiza. “CLINICAL-LABORATORY CHARACTERISTICS OF ENTEROVIRAL MENINGITIS WITHOUT PLEOCYTOSIS IN CHILDREN.” Халқаро илмий педиатрия журнали, 4(2), 928-934, 2025. https://doi.org/10.56121/2181-2926-2025-4-2-928-934
ChicagoAbdukadirova, Nargiza, Абдукадирова, Наргиза, and Abdukadirova, Nargiza. “CLINICAL-LABORATORY CHARACTERISTICS OF ENTEROVIRAL MENINGITIS WITHOUT PLEOCYTOSIS IN CHILDREN.” Халқаро илмий педиатрия журнали, 4(2), 928-934 (2025). https://doi.org/10.56121/2181-2926-2025-4-2-928-934
HarvardAbdukadirova, Nargiza, Абдукадирова, Наргиза, and Abdukadirova, Nargiza (2025) ‘CLINICAL-LABORATORY CHARACTERISTICS OF ENTEROVIRAL MENINGITIS WITHOUT PLEOCYTOSIS IN CHILDREN’, Халқаро илмий педиатрия журнали, 4(2), 928-934. https://doi.org/10.56121/2181-2926-2025-4-2-928-934
BibTeX
@article{abdukadirovanargiza2025,
  title = {CLINICAL-LABORATORY CHARACTERISTICS OF ENTEROVIRAL MENINGITIS WITHOUT PLEOCYTOSIS IN CHILDREN},
  author = {Abdukadirova, Nargiza and Абдукадирова, Наргиза and Abdukadirova, Nargiza},
  journal = {Халқаро илмий педиатрия журнали},
  year = {2025},
  volume = {4},
  number = {2},
  pages = {928-934},
  doi = {10.56121/2181-2926-2025-4-2-928-934},
  url = {https://doi.org/10.56121/2181-2926-2025-4-2-928-934}
}

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