Features of polymorphism of genes controlling the hemostasis system in deeply premature newborns with hemorrhagic disorders

Budalova , Anastasia, Kharlamova , Natalia, Fetisova , Irina, Ratnikova , Svetlana, Будалова , Анастасия, Харламова , Наталья, Фетисова , Ирина, Ратникова , Светлана, Budalova , Anastasia, Xarlamova , Natalya, Fetisova , Irina, Ratnikova , Svetlana

Халқаро илмий педиатрия журнали · 2022-yil

Annotatsiya

Currently, there is a need for a comprehensive assessment of the state of the hemostasis system in deeply premature newborns, including not only an assessment of the state of the vascular wall, platelet and plasma links of hemostasis, as well as the identification of features of polymorphism of genes controlling hemostasis. The identification of these features will help in predicting the development of hemorrhagic disorders in deeply premature newborns, which will make it possible to personalize the management tactics of this category of patients and reduce the rates of disability and infant mortality. In order to identify variants of polymorphism of genes of the hemostasis system in deeply premature newborns, a genetic examination of 99 children with a gestation period of up to 32 weeks was performed. With the definition of gene polymorphism: F2, F7, F13A1, FGB, ITGA2-a2, ITGB3-b3, PAI1. The study established combined variants of hemostasis gene polymorphism in children with hemorrhagic disorders, which can serve as a predictor of the formation of disorders in the hemostasis system.

Maqola ma’lumotlari
MualliflarBudalova , Anastasia, Kharlamova , Natalia, Fetisova , Irina, Ratnikova , Svetlana, Будалова , Анастасия, Харламова , Наталья, Фетисова , Ирина, Ратникова , Светлана, Budalova , Anastasia, Xarlamova , Natalya, Fetisova , Irina, Ratnikova , Svetlana
JurnalХалқаро илмий педиатрия журнали
NashriyotАндижон давлат тиббиёт институти; In Science МЧЖ
ISSN2181-2926, 2181-2926
Nashr sanasi2022-10-31
Jild1
Son6
Betlar20-25
TilIngliz
Ilmiy sohaTibbiyot
DOI10.56121/2181-2926-2022-6-20-25
Indeksga qo‘shilgan2026-08-26

DOI: 10.56121/2181-2926-2022-6-20-25 · Maqolaning asl sahifasi

Kalit so‘zlar

новорожденные, гены, система гемостаза, полиморфизм, геморрагические нарушения, newborns, genes, hemostasis system, polymorphism, hemorrhagic disorders, yangi tug'ilgan chaqaloqlar, genlar, gemostaz tizimi, polimorfizm, gemorragik kasalliklar

Ilmiy soha

Tibbiyot

Iqtibos keltirish

APABudalova , Anastasia, Kharlamova , Natalia, Fetisova , Irina, Ratnikova , Svetlana, Будалова , Анастасия, Харламова , Наталья, Фетисова , Ирина, Ратникова , Светлана, Budalova , Anastasia, Xarlamova , Natalya, Fetisova , Irina, & Ratnikova , Svetlana (2022). FEATURES OF POLYMORPHISM OF GENES CONTROLLING THE HEMOSTASIS SYSTEM IN DEEPLY PREMATURE NEWBORNS WITH HEMORRHAGIC DISORDERS. Халқаро илмий педиатрия журнали, 1(6), 20-25. https://doi.org/10.56121/2181-2926-2022-6-20-25
GOST (OAK)Budalova , Anastasia va b. FEATURES OF POLYMORPHISM OF GENES CONTROLLING THE HEMOSTASIS SYSTEM IN DEEPLY PREMATURE NEWBORNS WITH HEMORRHAGIC DISORDERS // Халқаро илмий педиатрия журнали. – 2022. – T. 1, № 6. – P. 20-25. – DOI: 10.56121/2181-2926-2022-6-20-25.
MLABudalova , Anastasia, Kharlamova , Natalia, Fetisova , Irina, Ratnikova , Svetlana, Будалова , Анастасия, Харламова , Наталья, Фетисова , Ирина, Ратникова , Светлана, Budalova , Anastasia, Xarlamova , Natalya, Fetisova , Irina, and Ratnikova , Svetlana. “FEATURES OF POLYMORPHISM OF GENES CONTROLLING THE HEMOSTASIS SYSTEM IN DEEPLY PREMATURE NEWBORNS WITH HEMORRHAGIC DISORDERS.” Халқаро илмий педиатрия журнали, 1(6), 20-25, 2022. https://doi.org/10.56121/2181-2926-2022-6-20-25
ChicagoBudalova , Anastasia, Kharlamova , Natalia, Fetisova , Irina, Ratnikova , Svetlana, Будалова , Анастасия, Харламова , Наталья, Фетисова , Ирина, Ратникова , Светлана, Budalova , Anastasia, Xarlamova , Natalya, Fetisova , Irina, and Ratnikova , Svetlana. “FEATURES OF POLYMORPHISM OF GENES CONTROLLING THE HEMOSTASIS SYSTEM IN DEEPLY PREMATURE NEWBORNS WITH HEMORRHAGIC DISORDERS.” Халқаро илмий педиатрия журнали, 1(6), 20-25 (2022). https://doi.org/10.56121/2181-2926-2022-6-20-25
HarvardBudalova , Anastasia, Kharlamova , Natalia, Fetisova , Irina, Ratnikova , Svetlana, Будалова , Анастасия, Харламова , Наталья, Фетисова , Ирина, Ратникова , Светлана, Budalova , Anastasia, Xarlamova , Natalya, Fetisova , Irina, and Ratnikova , Svetlana (2022) ‘FEATURES OF POLYMORPHISM OF GENES CONTROLLING THE HEMOSTASIS SYSTEM IN DEEPLY PREMATURE NEWBORNS WITH HEMORRHAGIC DISORDERS’, Халқаро илмий педиатрия журнали, 1(6), 20-25. https://doi.org/10.56121/2181-2926-2022-6-20-25
BibTeX
@article{budalovaanastasia2022,
  title = {FEATURES OF POLYMORPHISM OF GENES CONTROLLING THE HEMOSTASIS SYSTEM IN DEEPLY PREMATURE NEWBORNS WITH HEMORRHAGIC DISORDERS},
  author = {Budalova , Anastasia and Kharlamova , Natalia and Fetisova , Irina and Ratnikova , Svetlana and Будалова , Анастасия and Харламова , Наталья and Фетисова , Ирина and Ратникова , Светлана and Budalova , Anastasia and Xarlamova , Natalya and Fetisova , Irina and Ratnikova , Svetlana},
  journal = {Халқаро илмий педиатрия журнали},
  year = {2022},
  volume = {1},
  number = {6},
  pages = {20-25},
  doi = {10.56121/2181-2926-2022-6-20-25},
  url = {https://doi.org/10.56121/2181-2926-2022-6-20-25}
}

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