MRI-based morphological analysis and growth patterns of pituitary macroadenomas with different hormonal activity

MUKHAMMADOV, Nuriddin Askarovich, МУХАММАДОВ, Нуриддин Аскарович, MUHAMMADOV, Nuriddin Asqarovich

Research Focus · 2026-yil

Annotatsiya

Relevance. Pituitary macroadenomas are clinically significant mass lesions of the sellar and parasellar region. Their clinical course is determined not only by tumor size but also by hormonal activity, growth direction, cavernous sinus invasion, suprasellar extension, and anatomical relationship with the optic chiasm. Magnetic resonance imaging is the main instrumental diagnostic method for evaluating the morphological structure, topographic-anatomical characteristics, and extension of pituitary macroadenomas into adjacent structures. Materials and methods. The study proposes MRI-based morphological criteria for evaluating pituitary macroadenomas. The analyzed parameters included tumor size, suprasellar and parasellar extension, cavernous sinus invasion, Knosp grade, optic chiasm compression, pituitary stalk deviation, cystic degeneration, necrotic changes, and hemorrhagic components. Results. Functioning and non-functioning pituitary macroadenomas may differ in growth direction and degree of invasiveness. In particular, prolactinomas and somatotropinomas may demonstrate more pronounced lateral invasion into the cavernous sinus, whereas non-functioning macroadenomas more often present with suprasellar extension and optic chiasm compression. Conclusion. MRI-based morphological analysis is important for assessing the biological behavior of pituitary macroadenomas, estimating surgical risk, and individualizing treatment strategy.

Maqola ma’lumotlari
MualliflarMUKHAMMADOV, Nuriddin Askarovich, МУХАММАДОВ, Нуриддин Аскарович, MUHAMMADOV, Nuriddin Asqarovich
JurnalResearch Focus
NashriyotВетеринария ИТИ ва “Илм-фан ва инновациялар академияси” МЧЖ
ISSN2181-3833
Nashr sanasi2026-10-05
Jild5
Son9
Betlar24-32
TilIngliz
Ilmiy sohaVeterinariya
DOI10.66073/refocus.v5i9.0902
Indeksga qo‘shilgan2026-10-18

DOI: 10.66073/refocus.v5i9.0902 · Maqolaning asl sahifasi

Kalit so‘zlar

pituitary macroadenoma, MRI, hormonal activity, prolactinoma, somatotropinoma, cavernous sinus, Knosp classification, suprasellar growth, optic chiasm, gipofiz makroadenomasi, PitNET, magnit-rezonans tomografiya, gormonal faollik, prolaktinoma, somatotropinoma, kavernoz sinus, Knosp tasnifi, suprasellyar o‘sish, optik xiazma, макроаденома гипофиза, PitNET, магнитно-резонансная томография, гормональная активность, пролактинома, соматотропинома, кавернозный синус, классификация Knosp, супраселлярный рост, зрительная хиазма

Ilmiy soha

Veterinariya

Iqtibos keltirish

APAMUKHAMMADOV, Nuriddin Askarovich, МУХАММАДОВ, Нуриддин Аскарович, & MUHAMMADOV, Nuriddin Asqarovich (2026). MRI-based morphological analysis and growth patterns of pituitary macroadenomas with different hormonal activity. Research Focus, 5(9), 24-32. https://doi.org/10.66073/refocus.v5i9.0902
GOST (OAK)MUKHAMMADOV, Nuriddin Askarovich, МУХАММАДОВ, Нуриддин Аскарович, MUHAMMADOV, Nuriddin Asqarovich MRI-based morphological analysis and growth patterns of pituitary macroadenomas with different hormonal activity // Research Focus. – 2026. – T. 5, № 9. – P. 24-32. – DOI: 10.66073/refocus.v5i9.0902.
MLAMUKHAMMADOV, Nuriddin Askarovich, МУХАММАДОВ, Нуриддин Аскарович, and MUHAMMADOV, Nuriddin Asqarovich. “MRI-based morphological analysis and growth patterns of pituitary macroadenomas with different hormonal activity.” Research Focus, 5(9), 24-32, 2026. https://doi.org/10.66073/refocus.v5i9.0902
ChicagoMUKHAMMADOV, Nuriddin Askarovich, МУХАММАДОВ, Нуриддин Аскарович, and MUHAMMADOV, Nuriddin Asqarovich. “MRI-based morphological analysis and growth patterns of pituitary macroadenomas with different hormonal activity.” Research Focus, 5(9), 24-32 (2026). https://doi.org/10.66073/refocus.v5i9.0902
HarvardMUKHAMMADOV, Nuriddin Askarovich, МУХАММАДОВ, Нуриддин Аскарович, and MUHAMMADOV, Nuriddin Asqarovich (2026) ‘MRI-based morphological analysis and growth patterns of pituitary macroadenomas with different hormonal activity’, Research Focus, 5(9), 24-32. https://doi.org/10.66073/refocus.v5i9.0902
BibTeX
@article{mukhammadovnuriddinaskarovich2026,
  title = {MRI-based morphological analysis and growth patterns of pituitary macroadenomas with different hormonal activity},
  author = {MUKHAMMADOV, Nuriddin Askarovich and МУХАММАДОВ, Нуриддин Аскарович and MUHAMMADOV, Nuriddin Asqarovich},
  journal = {Research Focus},
  year = {2026},
  volume = {5},
  number = {9},
  pages = {24-32},
  doi = {10.66073/refocus.v5i9.0902},
  url = {https://doi.org/10.66073/refocus.v5i9.0902}
}

Boshqa maqola uchun iqtibos tayyorlash

Research Focus jurnalidan boshqa maqolalar

Research Focus — barcha maqolalar · 2026-yil arxivi

Veterinariya sohasidagi boshqa maqolalar

Veterinariya sohasidagi OAK jurnallari