Cardiovascular risk factors contribute to the development of cardiovascular disease and their presence may affect the level of microRNA expression in patients with ST-elevation myocardial infarction. So far, only a few reports have been published describing the relationship between microRNA expression and the presence of cardiovascular risk factors. Aim Evaluation of microRNA expression in patients with ST- elevation myocardial infarction with present cardiovascular risk factors. Materials & Methods Seventeen patients with ST-elevation myocardial infarction were examined. MicroRNA expression (miR-1, miR-208a i miR-423-5p) was determined according to the Pfaffla model and then compared between two groups: with and without cardiovascular risk factors. Results Higher expression levels of microRNAs were found in smokers. Lower levels of miR-1, miR-208a and miR-423-5p expression were found in patients with increased lipid levels or these using hypolipemic drugs. Conclusion MicroRNA expression in patients with ST-elevation myocardial infarction depends on the presence of some cardiovascular risk factors.
| Mualliflar | Edyta Nabiałek, Maciej Kaźmierski |
|---|---|
| Jurnal | Journal of cardiorespiratory research/Kardiorespirator tadqiqotlar jurnali |
| Nashr sanasi | 2022-10-07 |
| Jild | 3 |
| Son | 3 |
| Til | Rus |
сердечно-сосудистые факторы риска, микроРНК, инфаркт миокарда., Cardiovascular risk factors, microRNA, myocardial infarction, yurak-qon tomir xavf omillari, mikroRNK, miokard infarkti
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