Comparative characteristics of the parameters of the immune system of T- and B-lymphocytes showed the presence of an imbalance and tension in the immune system of patients with wound infection on the background of diabetes mellitus, which indicates the development of a systemic inflammatory reaction syndrome and the occurrence of gross immunological rearrangements reflected in the significant activity of lymphocytes with markers of early activation (CD25+ cells) and the readiness of cells to apoptosis (CD95+ cells), as well as natural killers (CD16+ cells). In patients with wound infection on the background of DM, in comparison with healthy people, it was shown that the content of all studied immunocompetent cells was significantly increased. This fact indicates that all lymphocytes are activated and the immune system is tense, which is associated with a sufficiently high number of pathogens in the focus and the development of systemic inflammatory reaction syndrome (SIRS) in patients, which in our opinion aggravates the course of the wound process.
| Mualliflar | Khamdamov , Bakhtiyor, Dekhonov , Aziz, Khamdamov , Alisherjon, Turayeva, Malika, Хамдамов , Бахтиёр, Дехконов , Азиз, Хамдамов , Алишержон, Тураева , Малика, Хамдамов , Бахтиёр, Деҳқонов , Азиз, Хамдамов , Алишержон, Тўраева, Малика |
|---|---|
| Jurnal | Профилактическая медицина и здоровье |
| Nashr sanasi | 2024-08-15 |
| Jild | 3 |
| Son | 4 |
| Betlar | 9-18 |
| Til | Rus |
иммунный профиль, раневая инфекция, сахарный диабет, immune profile, wound infection, diabetes mellitus, иммун ҳолат, жароҳат инфекциси, қандли диабет
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