Relevance. Congenital defects of the optic disc are the main risk factor for blindness and vision loss in 5–6% of cases in different countries, and the incidence of congenital defects of the optic nerve is 2–4%. In turn, genetic changes lead to the development of blindness in children in 50% of cases. Purpose of the study. To determine the features of the clinical picture of deprivation in children with congenital defects of the optic nerve head. Materials and methods. Research work was carried out in 2022–2023 in the city children's clinical hospital No. 1. The study analyzed electrophysiological and OCT images of 70 (118 eyes) children aged 3 to 18 years with a diagnosis of congenital optic disc hypoplasia (Q14.2) and 20 healthy children (40 eyes). Of the electrophysiological research methods, visual evoked potentials (VEP) were found using the Neuron-Spectrum 4-VPM apparatus, in the Stratus OST‑3 optical computed tomograph "Carl Zeiss Meditec" was regarded as the thickness of the nerve fibers of the retina. The results obtained were analyzed based on Student's t-test. The difference between the means was considered statistically significant at p≤0.05. Results and discussion. A unilateral decrease in the amplitude of the visual potentials (VP) P100 was noted in 75.3% of patients, a bilateral decrease in 24.7% of patients. A monocular decrease in amplitude indicated a unilateral prechiasmatic level of the lesion, while a bilateral decrease indicated bilateral disease. As a result of a comparative analysis, it was found that the indicators of visual acuity and the thickness of the retinal nerve fibers (TNFL; RNFL) are directly dependent on each other: the smaller the total average thickness of the TNFL of the injured eye, the lower the visual acuity. With hypoplasia of the optic disc (OPD), a statistically significant decrease in the diameter of the OPD (1.94±0.30 vs. 1.29±0.31 in normal) and physiological expansion (0.32±0.26 in normalvs. 0.65 ±0.41). In accordance with the above, it was noticed that their area also decreased. Results and conclusion. Once again, the importance of neurophysiological and neuroimaging examination methods such as optical coherence tomography and electroretinograms in the early detection of clinical signs of deprivation in situations where young children cannot give a subjective assessment of their condition, and an objective assessment of a doctor is difficult.
| Mualliflar | Э. Н. Билалов, Р. А. Закирходжаев, И. Р. Асрорхужаева |
|---|---|
| Jurnal | Передовая Офтальмология |
| Nashr sanasi | 2023-05-23 |
| Jild | 3 |
| Son | 3 |
| Betlar | 27-32 |
| Til | ru |
| DOI | 10.57231/j.ao.2023.3.3.006 |
DOI: 10.57231/j.ao.2023.3.3.006 · Maqolaning asl sahifasi
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