Relevance. Corneal pachymetry is one of the main criteria for diagnosing keratoconus. Using the most accurate and reliable measurement method allows for correct diagnosis and timely treatment. Purpose of the study. To compare optical coherence tomography (OCT) pachymetry and Scheimpflug keratotopography (SK) pachymetry data and establish their reliability, sensitivity and specificity for the diagnosis of keratoconus. Materials and methods. The study included 212 eyes (126 people), which were divided into two groups: the main group — patients with a confirmed diagnosis of grade 1–3 keratoconus. (according to Amsler.), and a control group of ophthalmologically healthy volunteers. All patients underwent a standard ophthalmological examination, as well as pachymetry using (SK) (TOMEY TMS‑5) and spectral OCT (SOCT Copernicus REVO 80). Results. In the main group, a statistically significant difference was obtained between measurement methods in terms of central corneal thickness (CCT) (p=0.02) and minimum corneal thickness (MCT) (p<0.001). In the control group, no significant differences were found between the two methods (CCT p = 0.63, MTP p = 0.34). ROC analysis for SK area under the curve (AUC) for CCT ≤516 was 0.896, Se=72.73, Sp=94.44. For MCT ≤508, the AUC was 0.933, Se=81.82, Sp=94.40. For OCT, respectively, CCT ≤515 AUC was 0.890, and Se=78.98, Sp=83.33. For MCT ≤497, AUC was 0.931, Se=84.66, Sp=86.11. Conclusion. He presence of significant differences in pachymetry measurements on SK and OCT in patients with keratoconus must be taken into account when making a diagnosis, dynamic monitoring and determining treatment tactics. It is recommended to monitor the disease using data from devices operating on the same principle. Data from SK pachymetry and spectral OCT are highly accurate diagnostic criteria for keratoconus with high sensitivity and specificity.
| Mualliflar | Л. А. Столярова, Т. А. Имшенецкая, Д. Е. Абельский |
|---|---|
| Jurnal | Передовая Офтальмология |
| Nashr sanasi | 2024-04-21 |
| Jild | 6 |
| Son | 6 |
| Betlar | 25-29 |
| Til | ru |
| DOI | 10.57231/j.ao.2023.6.6.005 |
DOI: 10.57231/j.ao.2023.6.6.005 · Maqolaning asl sahifasi
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