Options for Dealing with Pressure Dependence of Pulse Wave Velocity as a Measure of Arterial Stiffness: An Update of Cardio-Ankle Vascular Index (CAVI) and CAVI0

Bart Spronck, Tammo Delhaas, Mark Butlin, Koen D. Reesink, Alberto Avolio

PULSE · 2017-yil

Annotatsiya

Pulse wave velocity (PWV), a marker of arterial stiffness, is known to change instantaneously with changes in blood pressure. In this mini-review, we discuss two main approaches for handling the blood pressure dependence of PWV: (1) converting PWV into a pressure-independent index, and (2) correcting PWV per se for the pressure dependence. Under option 1, we focus on cardio-ankle vascular index (CAVI). CAVI is essentially a form of stiffness index β - CAVI is estimated for a (heart-to-ankle) trajectory, whereas β is estimated for a single artery from pressure and diameter measurements. Stiffness index β, and therefore also CAVI, have been shown to theoretically exhibit a slight residual blood pressure dependence due to the use of diastolic blood pressure instead of a fixed reference blood pressure. Additionally, CAVI exhibits pressure dependence due to the use of an estimated derivative of the pressure-diameter relationship. In this mini-review, we will address CAVI's blood pressure dependence theoretically, but also statistically. Furthermore, we review corrected indices (CAVI0 and β0) that theoretically do not show a residual blood pressure dependence. Under option 2, three ways of correcting PWV are reviewed: (1) using an exponential relationship between pressure and cross-sectional area, (2) by statistical model adjustment, and (3) through reference values or rule of thumb. Method 2 requires a population to be studied to characterise the statistical model, and method 3 requires a representative reference study. Given these limitations, method 1 seems preferable for correcting PWV per se for its blood pressure dependence. In summary, several options are available to handle the blood pressure dependence of PWV. If a blood pressure-independent index is sought, CAVI0 is theoretically preferable over CAVI. If correcting PWV per se is required, using an exponential pressure-area relationship provides the user with a method to correct PWV on an individual basis.

Maqola ma’lumotlari
MualliflarBart Spronck, Tammo Delhaas, Mark Butlin, Koen D. Reesink, Alberto Avolio
JurnalPULSE
NashriyotPROFI университетининг
ISSN2074-1855, 2235-8668
Nashr sanasi2017-01-01
Jild5
Son1-4
Betlar106-114
TilIngliz
Ilmiy sohaPsixologiya
DOI10.1159/000479322
Indeksga qo‘shilgan2026-09-02

DOI: 10.1159/000479322 · Maqolaning asl sahifasi · PDF

Ilmiy soha

Psixologiya

Iqtibos keltirish

APABart Spronck, Tammo Delhaas, Mark Butlin, Koen D. Reesink, & Alberto Avolio (2017). Options for Dealing with Pressure Dependence of Pulse Wave Velocity as a Measure of Arterial Stiffness: An Update of Cardio-Ankle Vascular Index (CAVI) and CAVI0. PULSE, 5(1-4), 106-114. https://doi.org/10.1159/000479322
GOST (OAK)Bart Spronck va b. Options for Dealing with Pressure Dependence of Pulse Wave Velocity as a Measure of Arterial Stiffness: An Update of Cardio-Ankle Vascular Index (CAVI) and CAVI0 // PULSE. – 2017. – T. 5, № 1-4. – P. 106-114. – DOI: 10.1159/000479322.
MLABart Spronck, Tammo Delhaas, Mark Butlin, Koen D. Reesink, and Alberto Avolio. “Options for Dealing with Pressure Dependence of Pulse Wave Velocity as a Measure of Arterial Stiffness: An Update of Cardio-Ankle Vascular Index (CAVI) and CAVI0.” PULSE, 5(1-4), 106-114, 2017. https://doi.org/10.1159/000479322
ChicagoBart Spronck, Tammo Delhaas, Mark Butlin, Koen D. Reesink, and Alberto Avolio. “Options for Dealing with Pressure Dependence of Pulse Wave Velocity as a Measure of Arterial Stiffness: An Update of Cardio-Ankle Vascular Index (CAVI) and CAVI0.” PULSE, 5(1-4), 106-114 (2017). https://doi.org/10.1159/000479322
HarvardBart Spronck, Tammo Delhaas, Mark Butlin, Koen D. Reesink, and Alberto Avolio (2017) ‘Options for Dealing with Pressure Dependence of Pulse Wave Velocity as a Measure of Arterial Stiffness: An Update of Cardio-Ankle Vascular Index (CAVI) and CAVI0’, PULSE, 5(1-4), 106-114. https://doi.org/10.1159/000479322
BibTeX
@article{bartspronck2017,
  title = {Options for Dealing with Pressure Dependence of Pulse Wave Velocity as a Measure of Arterial Stiffness: An Update of Cardio-Ankle Vascular Index (CAVI) and CAVI0},
  author = {Bart Spronck and Tammo Delhaas and Mark Butlin and Koen D. Reesink and Alberto Avolio},
  journal = {PULSE},
  year = {2017},
  volume = {5},
  number = {1-4},
  pages = {106-114},
  doi = {10.1159/000479322},
  url = {https://doi.org/10.1159/000479322}
}

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