Microvascular Function and Exercise Training: Functional Implication of Nitric Oxide Signaling and Ion Channels

Junyoung Hong, Yoonjung Park

PULSE · 2024-yil

Annotatsiya

Background: Exercise training elicits indubitable positive adaptation in microcirculation in health and disease populations. An inclusive overview of the current knowledge regarding the effects of exercise on microvascular function consolidates an in-depth understanding of microvasculature. Summary: The main physiological function of microvasculature is to maintain optimal blood flow regulation to supply oxygen and nutrition during elevated physical demands in the cardiovascular system. There are several cellular and molecular alterations in resistance vessels in response to exercise intervention, an increase in nitric oxide-mediated vasodilation through the regulation of oxidative stress, inflammatory response, and ion channels in endothelial cells, thus increasing myogenic tone via voltage-gated Ca2+ channels in smooth muscle cells. Key Messages: In the review, we postulate that exercise should be considered a medicine for people with diverse diseases through a comprehensive understanding of the cellular and molecular underlying mechanisms in microcirculation through exercise training.

Maqola ma’lumotlari
MualliflarJunyoung Hong, Yoonjung Park
JurnalPULSE
NashriyotPROFI университетининг
ISSN2074-1855, 2235-8668
Nashr sanasi2024-01-01
Jild12
Son1
Betlar27-33
TilIngliz
Ilmiy sohaPsixologiya
DOI10.1159/000538271
Indeksga qo‘shilgan2026-09-02

DOI: 10.1159/000538271 · Maqolaning asl sahifasi

Ilmiy soha

Psixologiya

Iqtibos keltirish

APAJunyoung Hong, & Yoonjung Park (2024). Microvascular Function and Exercise Training: Functional Implication of Nitric Oxide Signaling and Ion Channels. PULSE, 12(1), 27-33. https://doi.org/10.1159/000538271
GOST (OAK)Junyoung Hong, Yoonjung Park Microvascular Function and Exercise Training: Functional Implication of Nitric Oxide Signaling and Ion Channels // PULSE. – 2024. – T. 12, № 1. – P. 27-33. – DOI: 10.1159/000538271.
MLAJunyoung Hong, and Yoonjung Park. “Microvascular Function and Exercise Training: Functional Implication of Nitric Oxide Signaling and Ion Channels.” PULSE, 12(1), 27-33, 2024. https://doi.org/10.1159/000538271
ChicagoJunyoung Hong, and Yoonjung Park. “Microvascular Function and Exercise Training: Functional Implication of Nitric Oxide Signaling and Ion Channels.” PULSE, 12(1), 27-33 (2024). https://doi.org/10.1159/000538271
HarvardJunyoung Hong, and Yoonjung Park (2024) ‘Microvascular Function and Exercise Training: Functional Implication of Nitric Oxide Signaling and Ion Channels’, PULSE, 12(1), 27-33. https://doi.org/10.1159/000538271
BibTeX
@article{junyounghong2024,
  title = {Microvascular Function and Exercise Training: Functional Implication of Nitric Oxide Signaling and Ion Channels},
  author = {Junyoung Hong and Yoonjung Park},
  journal = {PULSE},
  year = {2024},
  volume = {12},
  number = {1},
  pages = {27-33},
  doi = {10.1159/000538271},
  url = {https://doi.org/10.1159/000538271}
}

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