Sickle Cell Disease-Induced Pulmonary Hypertension: A Review of Pathophysiology, Management, and Current Literature

Abu Baker Sheikh, Adeel Nasrullah, Erick Daniel Lopez, Mian Tanveer Ud Din, Shazib Sagheer, Ishan Shah, Nismat Javed, Rahul Shekhar

PULSE · 2021-yil

Annotatsiya

Sickle cell disease is an inherited hemoglobinopathy leading to the synthesis of hemoglobin S. Hemoglobin S results in the formation of abnormal sickle-shaped erythrocytes that lead to hematologic abnormalities such as hemolytic anemia and increased risks of thrombosis. Another particular problem encountered with the disease is pulmonary hypertension. The objective of this narrative review is to discuss the prevalence, pathophysiology mechanisms, diagnostic techniques, treatment options, and prognostic indicators in the setting of sickle cell disease with pulmonary hypertension. Additionally, the review also highlights other advancements that are being investigated. Considering the significant morbidity, mortality, and prevalence of pulmonary hypertension in patients with sickle cell disease, it is important to account for the aforementioned domains in the future guidelines to provide optimal and individualized care to the high-risk individuals as well as reduce the progression of disease, morbidity, and mortality rates.

Maqola ma’lumotlari
MualliflarAbu Baker Sheikh, Adeel Nasrullah, Erick Daniel Lopez, Mian Tanveer Ud Din, Shazib Sagheer, Ishan Shah, Nismat Javed, Rahul Shekhar
JurnalPULSE
NashriyotPROFI университетининг
ISSN2074-1855, 2235-8668
Nashr sanasi2021-01-01
Jild9
Son3-4
Betlar57-63
TilIngliz
Ilmiy sohaPsixologiya
DOI10.1159/000519101
Indeksga qo‘shilgan2026-09-02

DOI: 10.1159/000519101 · Maqolaning asl sahifasi

Ilmiy soha

Psixologiya

Iqtibos keltirish

APAAbu Baker Sheikh, Adeel Nasrullah, Erick Daniel Lopez, Mian Tanveer Ud Din, Shazib Sagheer, Ishan Shah, Nismat Javed, & Rahul Shekhar (2021). Sickle Cell Disease-Induced Pulmonary Hypertension: A Review of Pathophysiology, Management, and Current Literature. PULSE, 9(3-4), 57-63. https://doi.org/10.1159/000519101
GOST (OAK)Abu Baker Sheikh va b. Sickle Cell Disease-Induced Pulmonary Hypertension: A Review of Pathophysiology, Management, and Current Literature // PULSE. – 2021. – T. 9, № 3-4. – P. 57-63. – DOI: 10.1159/000519101.
MLAAbu Baker Sheikh, Adeel Nasrullah, Erick Daniel Lopez, Mian Tanveer Ud Din, Shazib Sagheer, Ishan Shah, Nismat Javed, and Rahul Shekhar. “Sickle Cell Disease-Induced Pulmonary Hypertension: A Review of Pathophysiology, Management, and Current Literature.” PULSE, 9(3-4), 57-63, 2021. https://doi.org/10.1159/000519101
ChicagoAbu Baker Sheikh, Adeel Nasrullah, Erick Daniel Lopez, Mian Tanveer Ud Din, Shazib Sagheer, Ishan Shah, Nismat Javed, and Rahul Shekhar. “Sickle Cell Disease-Induced Pulmonary Hypertension: A Review of Pathophysiology, Management, and Current Literature.” PULSE, 9(3-4), 57-63 (2021). https://doi.org/10.1159/000519101
HarvardAbu Baker Sheikh, Adeel Nasrullah, Erick Daniel Lopez, Mian Tanveer Ud Din, Shazib Sagheer, Ishan Shah, Nismat Javed, and Rahul Shekhar (2021) ‘Sickle Cell Disease-Induced Pulmonary Hypertension: A Review of Pathophysiology, Management, and Current Literature’, PULSE, 9(3-4), 57-63. https://doi.org/10.1159/000519101
BibTeX
@article{abubakersheikh2021,
  title = {Sickle Cell Disease-Induced Pulmonary Hypertension: A Review of Pathophysiology, Management, and Current Literature},
  author = {Abu Baker Sheikh and Adeel Nasrullah and Erick Daniel Lopez and Mian Tanveer Ud Din and Shazib Sagheer and Ishan Shah and Nismat Javed and Rahul Shekhar},
  journal = {PULSE},
  year = {2021},
  volume = {9},
  number = {3-4},
  pages = {57-63},
  doi = {10.1159/000519101},
  url = {https://doi.org/10.1159/000519101}
}

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