Genome-wide association studies (GWAS) have greatly expanded our understanding of the genetic architecture of cardiovascular diseases in the past decade. They have revealed hundreds of suggestive genetic loci that replicate known biological candidate genes and indicate the existence of a previously unsuspected new biology relevant to cardiovascular disorders. These data have been used successfully to create genetic risk scores that may improve risk prediction and the identification of susceptive individuals. Furthermore, these GWAS-identified novel pathways may herald a new era of novel drug development and stratification of patients. In this review, we will briefly summarize the literature on the candidate genes and signals discovered by GWAS on hypertension and coronary artery disease and discuss their implications on clinical medicine.
| Mualliflar | Yan Wang, Ji‐Guang Wang |
|---|---|
| Jurnal | PULSE |
| Nashriyot | PROFI университетининг |
| ISSN | 2074-1855, 2235-8668 |
| Nashr sanasi | 2018-01-01 |
| Jild | 6 |
| Son | 3-4 |
| Betlar | 169-186 |
| Til | Ingliz |
| Ilmiy soha | Psixologiya |
| DOI | 10.1159/000496150 |
| Indeksga qo‘shilgan | 2026-09-02 |
DOI: 10.1159/000496150 · Maqolaning asl sahifasi
| APA | Yan Wang, & Ji‐Guang Wang (2018). Genome-Wide Association Studies of Hypertension and Several Other Cardiovascular Diseases. PULSE, 6(3-4), 169-186. https://doi.org/10.1159/000496150 |
|---|---|
| GOST (OAK) | Yan Wang, Ji‐Guang Wang Genome-Wide Association Studies of Hypertension and Several Other Cardiovascular Diseases // PULSE. – 2018. – T. 6, № 3-4. – P. 169-186. – DOI: 10.1159/000496150. |
| MLA | Yan Wang, and Ji‐Guang Wang. “Genome-Wide Association Studies of Hypertension and Several Other Cardiovascular Diseases.” PULSE, 6(3-4), 169-186, 2018. https://doi.org/10.1159/000496150 |
| Chicago | Yan Wang, and Ji‐Guang Wang. “Genome-Wide Association Studies of Hypertension and Several Other Cardiovascular Diseases.” PULSE, 6(3-4), 169-186 (2018). https://doi.org/10.1159/000496150 |
| Harvard | Yan Wang, and Ji‐Guang Wang (2018) ‘Genome-Wide Association Studies of Hypertension and Several Other Cardiovascular Diseases’, PULSE, 6(3-4), 169-186. https://doi.org/10.1159/000496150 |
| BibTeX | @article{yanwang2018,
title = {Genome-Wide Association Studies of Hypertension and Several Other Cardiovascular Diseases},
author = {Yan Wang and Ji‐Guang Wang},
journal = {PULSE},
year = {2018},
volume = {6},
number = {3-4},
pages = {169-186},
doi = {10.1159/000496150},
url = {https://doi.org/10.1159/000496150}
} |
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