Synthesis n-oxides of pyridylacethylene amines based on 2-methyl-5-ethynylpyridine

IKRAMOV, Abduvakhab, ZIYADULLAYEV, Odiljon, KHAMIDJANOV, Adkham, BOJARIEV, Shavkat, KHANDAMOV, Davron

Kimyo va kimyo texnologiyasi · 2021-yil

Annotatsiya

The aim of this work is to study the reaction of 2-methyl-5-ethynylpyridine N-oxide with some aliphatic and aromatic amines to obtain N-oxides of pyridylacetylenic amines. 2-Methyl-5-ethylpyridine converted to 2-methyl-5-vinylpyridine by dehydrogenation, and 2-methyl-5-ethynylpyridine obtained by bromination and dehydrobromination. 2-methyl-5-ethynylpyridine N-oxide synthesized by oxidation of 2-methyl-5-ethynylpyridine with perhydrol in acetic anhydride. The synthesis of N-oxides of pyridylacetylenic amines by the Mannich reaction carried out. The effect of the solvents: methanol, ethanol and n-dioxane, the catalyst, and the reaction time on the yield of the final product studied. The structure and composition of the synthesized PAA N-oxides were established using IR and PMR spectroscopy.

Maqola ma’lumotlari
MualliflarIKRAMOV, Abduvakhab, ZIYADULLAYEV, Odiljon, KHAMIDJANOV, Adkham, BOJARIEV, Shavkat, KHANDAMOV, Davron
JurnalKimyo va kimyo texnologiyasi
Nashr sanasi2021-04-25
Betlar48-53
Tilen
DOI10.51348/lupi3276

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