Solvent effect on the molecular properties of paracetamol

Utkirjon Holikulov, A. Jumabaev, B. Khudaykulov, Sh. Yormatov, А. Р. Сафаров

Samarqand davlat universiteti ilmiy tadqiqotlar axborotnomasi · 2025-yil

Annotatsiya

In this study, the effect of different solvent phases (water, DMSO, acetonitrile, ethanol, chloroform and heptane) on the electronic, reactivity and nonlinear optical (NLO) properties of paracetamol was analyzed using quantum mechanical calculations. Quantum mechanical calculations were performed using the density functional theory (DFT) method with the B3LYP function and the 6-311++G(d,p) basis set. The calculation results showed that the smallest dipole moment for the paracetamol molecule is 2.62 D in the heptane phase, and the largest dipole moment is 3.36 D in the water phase.

Maqola ma’lumotlari
MualliflarUtkirjon Holikulov, A. Jumabaev, B. Khudaykulov, Sh. Yormatov, А. Р. Сафаров
JurnalSamarqand davlat universiteti ilmiy tadqiqotlar axborotnomasi
Nashr sanasi2025-06-01
Jild1
Son3
Betlar29-35
Tilen
DOI10.59251/2181-3973.2025.v1.138.1.3416

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