The involvement of melatonin levels in the development of severe epilepsy, insomnia and deterioration in quality of life with diagnostically significant melatonin levels >55 pg/ml is scientifically substantiated. The obtained data were confirmed by correlation analysis and high sensitivity (Sе=91.5%) and specificity (Sp=86.4%), i.e. in 91.5% of cases, positive test results will allow to correctly diagnose the risk of insomnia and deterioration in quality of life. The conducted correlation analysis showed a reliable relationship between the subscales of the QOLIE-31 questionnaire and the degree of daytime sleepiness at rest or during active activity, as well as with the indicators of the subjective characteristics of sleep scale, difficulty maintaining sleep, sleep disturbance and anxiety level.
| Mualliflar | Kalandarova S.Kh |
|---|---|
| Jurnal | Klinik fanlar yilnomasi |
| Nashr sanasi | 2025-11-12 |
| Jild | 2 |
| Son | 3/2 |
| Til | Rus |
epilepsy associated with sleep, the effect of melatonin on sleep, quality of life, эпилепсия, ассоциированное со сном, влияние мелатонина на сон, качество жизни, uyqu bilan bog‘liq epilepsiya, melatoninning uyquga ta’siri, hayot sifati
For several thousand years, various methods of surgical treatment of congenital cleft lip and palate have been used. But despite this, the treatment of these pathologies is still a difficult task for surgeons. In this…
While the hepatotoxicity of anti-tuberculosis therapy is well-documented, its direct impact on liver fibrogenesis requires clarification. The aim of this study was to comparatively evaluate the levels of key markers of…
The optimal cut-off points for satiety and fasting were 145 mg/dl and 110 mg/dl, with C-statistics of 0.594 and 0.626, Youden index of 0.187 and 0.252, and Harrell's fit statistic of 0.590 and 0.630. The corresponding…
In recent studies, obesity has been associated with a decrease in microbial diversity and a decrease in the species richness of the microbiota. A study was conducted where two groups were included: the main group - 60…
This article explores the effects of hormonal changes on oral health in women of reproductive age preparing for pregnancy. Fluctuations in estrogen and progesterone levels can significantly affect the oral mucosa…
This study was performed on the basis of the coloproctology department of the Republican Medical Specialized Scientific and Practical Center of Oncology and Radiology in Tashkent. Locally advanced colon and rectosigmoid…
Secondary cataract (secondary clouding of the posterior lens capsule) is a frequent complication after surgical treatment of cataracts in children. Nd:YAG laser capsulotomy (Nd:YAG-LC) has proven itself as an effective…
Arterial hypertension is one of the most common and fatal diseases in the world, including in our republic. When chronic obstructive pulmonary disease is accompanied by arterial hypertension and is accompanied by renal…
Necrotizing enterocolitis (NEC) is a severe gastrointestinal disease that primarily affects premature infants. It is characterized by inflammation, ischemia, and necrosis of the intestinal wall. This article examines…
Febrile seizures are generalized seizures, usually in children between the ages of 6 months and 5 years. Despite the relatively favorable prognosis, FS often causes significant anxiety among parents and may be…