ADVANCED DIAGNOSTIC APPROACHES IN THE IDENTIFICATION AND MANAGEMENT OF MYCOPLASMA PNEUMONIA IN CHILDREN

Kholikova G.A.

Вестник Ассоциации пульмонологов Центральной Азии · 2026-yil

Annotatsiya

Delayed detection of atypical forms of community-acquired pneumonia (CAP) in children remains one of the most pressing issues in modern pediatrics, leading to prolonged treatment duration. This is largely associated with insufficient early diagnosis at the level of family polyclinics and primary healthcare institutions, incorrect clinical assessment, inappropriate therapeutic strategies, delayed initiation of treatment, and late hospital admission of patients.Aim of the Study. The aim of this study was to identify the clinical, laboratory, and instrumental features of atypical pneumonia in children in order to optimize diagnostic accuracy and improve treatment strategies.Materials and Methods. The study was conducted during the autumn–winter period of 2024 among 160 children aged from 3 months to 16 years admitted to the regional multidisciplinary pediatric medical center. Of these, 128 children were referred by primary healthcare institutions with a diagnosis of community-acquired pneumonia. The remaining 32 patients had previously received outpatient antibacterial therapy for acute respiratory infections without clinical improvement and were hospitalized on days 7–9 of illness. Results. Out of 160 examined children, pneumonia was clinically confirmed in 132 cases (82.5%). In 28 patients (17.5%), pneumonia was not confirmed after radiological examination. Among these cases, obstructive bronchitis was diagnosed in 42.8%, bronchiolitis in 17.6%, acute respiratory viral infections in 21.4%, and influenza in 17.6%. Among the confirmed cases, PCR and ELISA testing identified Mycoplasma pneumoniae in 46 children, accounting for 34.8% of cases. IgM antibodies were detected in 42.4% of patients, indicating active infection. IgG antibodies to Chlamydia were detected in 3% of cases, suggesting prior exposure. It was also observed that atypical pneumonia was more common in children who were prematurely born, artificially fed, or had a history of rickets.Conclusion. Mycoplasma pneumoniae is one of the most common causative agents of atypical pneumonia in children, particularly in those older than 5 years.

Maqola ma’lumotlari
MualliflarKholikova G.A.
JurnalВестник Ассоциации пульмонологов Центральной Азии
Nashr sanasi2026-05-18
Jild19
Son14
Betlar47-51
TilRus

Kalit so‘zlar

Typical and atypical types of community-acquired pneumonia (CAP), clinical manifestations of (CAP), children, polymerase chain reaction (PCR), enzyme-linked immunosorbent assay (ELISA) method.

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