Development of a purification technology for pharmaceutical-grade sodium carboxymethyl cellulose (na-cmc) from mashar STEM cellulose for medical gypsum applications

Sattorov, Laziz Xolmurodovich, Kurbanov, Abdiraxim Axmedovich, Rahmatov, Xudoyor Boboniyozovich, Jurayeva, Huriyat Zoirovna, Сатторов, Лазиз Холмуродович, Курбанов, Абдирахим Ахмедович, Рахматов, Худоёр Бобониёзович, Джураева, Хурият Зоировна, Sattorov, Laziz Xolmurodovich, Kurbanov, Abdiraxim Axmedovich, Rahmatov, Xudoyor Boboniyozovich, Jurayeva, Huriyat Zoirovna

Саноатда рақамли технологиялар · 2026-yil

Annotatsiya

This study presents a technology for producing highly purified sodium carboxymethyl cellulose (Na-CMC) from cellulose extracted from locally available mashar stems for medical applications, particularly in the manufacture of medical gypsum. Technical Na-CMC was purified by ethanol extraction using a 53% aqueous ethanol solution, and the influence of extraction time on the purity and quality of the final product was systematically investigated. The optimum extraction time was found to be 40 min, resulting in a maximum main substance content of 99%. The physicochemical properties of the purified Na-CMC, including degree of substitution, dynamic viscosity, water solubility, and pH, were determined and compared with the requirements of relevant technical standards. X-ray diffraction (XRD) analysis confirmed the successful structural transformation of cellulose into Na-CMC through a reduction in crystallinity after carboxymethylation. The results demonstrate that mashar stem cellulose is a promising renewable local raw material for the production of pharmaceutical-grade Na-CMC with properties suitable for medical gypsum and other biomedical applications.

Maqola ma’lumotlari
MualliflarSattorov, Laziz Xolmurodovich, Kurbanov, Abdiraxim Axmedovich, Rahmatov, Xudoyor Boboniyozovich, Jurayeva, Huriyat Zoirovna, Сатторов, Лазиз Холмуродович, Курбанов, Абдирахим Ахмедович, Рахматов, Худоёр Бобониёзович, Джураева, Хурият Зоировна, Sattorov, Laziz Xolmurodovich, Kurbanov, Abdiraxim Axmedovich, Rahmatov, Xudoyor Boboniyozovich, Jurayeva, Huriyat Zoirovna
JurnalСаноатда рақамли технологиялар
NashriyotҚарши муҳандислик-иқтисодиёт институти
ISSN3030-3214, 2023-2026
Nashr sanasi2026-06-29
Jild4
Son2
Betlar186-192
TilIngliz
DOI10.70769/3030-3214.srt.4.2.2026.30
Indeksga qo‘shilgan2026-09-06

DOI: 10.70769/3030-3214.srt.4.2.2026.30 · Maqolaning asl sahifasi

Kalit so‘zlar

Na-CMC, mashar stem, cellulose, ethanol extraction, medical gypsum, X-ray diffraction, physicochemical properties, Na-CMC, стебель машара, целлюлоза, этанольная экстракция, медицинский гипс, XRD-анализ, физико-химические свойства, Na-CMC, mashar poyasi, sellyuloza, etanol ekstraksiyasi, tibbiy gips, XRD tahlili, fizik-kimyoviy xossalar

Iqtibos keltirish

APASattorov, Laziz Xolmurodovich, Kurbanov, Abdiraxim Axmedovich, Rahmatov, Xudoyor Boboniyozovich, Jurayeva, Huriyat Zoirovna, Сатторов, Лазиз Холмуродович, Курбанов, Абдирахим Ахмедович, Рахматов, Худоёр Бобониёзович, Джураева, Хурият Зоировна, Sattorov, Laziz Xolmurodovich, Kurbanov, Abdiraxim Axmedovich, Rahmatov, Xudoyor Boboniyozovich, & Jurayeva, Huriyat Zoirovna (2026). DEVELOPMENT OF A PURIFICATION TECHNOLOGY FOR PHARMACEUTICAL-GRADE SODIUM CARBOXYMETHYL CELLULOSE (NA-CMC) FROM MASHAR STEM CELLULOSE FOR MEDICAL GYPSUM APPLICATIONS. Саноатда рақамли технологиялар, 4(2), 186-192. https://doi.org/10.70769/3030-3214.srt.4.2.2026.30
GOST (OAK)Sattorov, Laziz Xolmurodovich va b. DEVELOPMENT OF A PURIFICATION TECHNOLOGY FOR PHARMACEUTICAL-GRADE SODIUM CARBOXYMETHYL CELLULOSE (NA-CMC) FROM MASHAR STEM CELLULOSE FOR MEDICAL GYPSUM APPLICATIONS // Саноатда рақамли технологиялар. – 2026. – T. 4, № 2. – P. 186-192. – DOI: 10.70769/3030-3214.srt.4.2.2026.30.
MLASattorov, Laziz Xolmurodovich, Kurbanov, Abdiraxim Axmedovich, Rahmatov, Xudoyor Boboniyozovich, Jurayeva, Huriyat Zoirovna, Сатторов, Лазиз Холмуродович, Курбанов, Абдирахим Ахмедович, Рахматов, Худоёр Бобониёзович, Джураева, Хурият Зоировна, Sattorov, Laziz Xolmurodovich, Kurbanov, Abdiraxim Axmedovich, Rahmatov, Xudoyor Boboniyozovich, and Jurayeva, Huriyat Zoirovna. “DEVELOPMENT OF A PURIFICATION TECHNOLOGY FOR PHARMACEUTICAL-GRADE SODIUM CARBOXYMETHYL CELLULOSE (NA-CMC) FROM MASHAR STEM CELLULOSE FOR MEDICAL GYPSUM APPLICATIONS.” Саноатда рақамли технологиялар, 4(2), 186-192, 2026. https://doi.org/10.70769/3030-3214.srt.4.2.2026.30
ChicagoSattorov, Laziz Xolmurodovich, Kurbanov, Abdiraxim Axmedovich, Rahmatov, Xudoyor Boboniyozovich, Jurayeva, Huriyat Zoirovna, Сатторов, Лазиз Холмуродович, Курбанов, Абдирахим Ахмедович, Рахматов, Худоёр Бобониёзович, Джураева, Хурият Зоировна, Sattorov, Laziz Xolmurodovich, Kurbanov, Abdiraxim Axmedovich, Rahmatov, Xudoyor Boboniyozovich, and Jurayeva, Huriyat Zoirovna. “DEVELOPMENT OF A PURIFICATION TECHNOLOGY FOR PHARMACEUTICAL-GRADE SODIUM CARBOXYMETHYL CELLULOSE (NA-CMC) FROM MASHAR STEM CELLULOSE FOR MEDICAL GYPSUM APPLICATIONS.” Саноатда рақамли технологиялар, 4(2), 186-192 (2026). https://doi.org/10.70769/3030-3214.srt.4.2.2026.30
HarvardSattorov, Laziz Xolmurodovich, Kurbanov, Abdiraxim Axmedovich, Rahmatov, Xudoyor Boboniyozovich, Jurayeva, Huriyat Zoirovna, Сатторов, Лазиз Холмуродович, Курбанов, Абдирахим Ахмедович, Рахматов, Худоёр Бобониёзович, Джураева, Хурият Зоировна, Sattorov, Laziz Xolmurodovich, Kurbanov, Abdiraxim Axmedovich, Rahmatov, Xudoyor Boboniyozovich, and Jurayeva, Huriyat Zoirovna (2026) ‘DEVELOPMENT OF A PURIFICATION TECHNOLOGY FOR PHARMACEUTICAL-GRADE SODIUM CARBOXYMETHYL CELLULOSE (NA-CMC) FROM MASHAR STEM CELLULOSE FOR MEDICAL GYPSUM APPLICATIONS’, Саноатда рақамли технологиялар, 4(2), 186-192. https://doi.org/10.70769/3030-3214.srt.4.2.2026.30
BibTeX
@article{sattorovlazizxolmurodovich2026,
  title = {DEVELOPMENT OF A PURIFICATION TECHNOLOGY FOR PHARMACEUTICAL-GRADE SODIUM CARBOXYMETHYL CELLULOSE (NA-CMC) FROM MASHAR STEM CELLULOSE FOR MEDICAL GYPSUM APPLICATIONS},
  author = {Sattorov, Laziz Xolmurodovich and Kurbanov, Abdiraxim Axmedovich and Rahmatov, Xudoyor Boboniyozovich and Jurayeva, Huriyat Zoirovna and Сатторов, Лазиз Холмуродович and Курбанов, Абдирахим Ахмедович and Рахматов, Худоёр Бобониёзович and Джураева, Хурият Зоировна and Sattorov, Laziz Xolmurodovich and Kurbanov, Abdiraxim Axmedovich and Rahmatov, Xudoyor Boboniyozovich and Jurayeva, Huriyat Zoirovna},
  journal = {Саноатда рақамли технологиялар},
  year = {2026},
  volume = {4},
  number = {2},
  pages = {186-192},
  doi = {10.70769/3030-3214.srt.4.2.2026.30},
  url = {https://doi.org/10.70769/3030-3214.srt.4.2.2026.30}
}

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