MOLECULAR-NEUROPHYSIOLOGICAL INTERACTIONS IN THE FORMATION OF CHRONIC NEUROPATHIC PAIN SYNDROME: CLINICAL AND DIAGNOSTIC APPROACHES (literature review)
Chronic neuropathic pain syndrome is one of the most complex and socially significant problems of modern medicine, affecting 6.9% to 10% of the adult population in developed countries. The pathophysiology of neuropathic pain is characterized by complex multi-level processes, including peripheral and central sensitization, neuroimmune interactions, and the disregulation of descending modulatory systems.
Гайбиев Акмал Ахматжонович, Бободжонов Шахбоз Абдусодикович · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-09-12
Metabolic syndrome (MS) is a complex of interconnected metabolic disorders, including abdominal obesity, insulin resistance, dyslipidemia, and arterial hypertension. In recent decades, there has been a significant…
Саноева Матлюба Жахонкуловна, Намозова Хурмат Жалиловна · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-09-12
Purpose. Study of the structure of neuropsychological damage depending on the stages of chronic cerebral ischemia (CCI), analysis of causes and factors. Materials and methods. 172 (100%) patients underwent neurological…
Адамбаев Зуфар Ибрагимович, Киличев Ибодулла Абдуллаевич, Олмосов Ровшан Шерали угли · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-09-12
The article addresses the role of visual evoked potentials (VEPs) in diagnosing demyelinating processes of the optic nerve. The study aims to systematize VEP data, integrate existing evidence with clinical observations…
Собирова Донохон Саидаскархановна · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-09-12
Post-stroke epilepsy is one of the most significant complications of stroke, exerting a negative impact on the recovery of cognitive and motor functions as well as on patients’ quality of life. Despite the accumulated…
Иноятова Ситора Ойбековна · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-09-12
The article investigates the role of synergistic interactions between polymorphisms in the genes SOD2 (Ala16Val), EDN1 (Lys197Asn), and eNOS (T786C) in the development of cerebrovascular diseases (CVD). The primary…
Ахмаджон Абдумаъруф исок угли, Мавлянова Зилола Фархадовна, Ким Ольга Анатольевна · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-09-12
The aim of the research: development and testing of personalized programs aimed at correcting biomechanical disorders, reducing neurological manifestations and improving the quality of life of patients. Materials and…
Дилшода Турдикуловна Акрамова · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-09-12
This study investigates the relationship between serum neurofilament light chain levels and clinical parameters in patients with Parkinson’s disease and Parkinsonism syndromes. The analysis included motor and cognitive…
Олимов Жахонгир Абдуазимжон угли, Абдукаюмов Абдуманноп Абдумаджидович, Мусаев Абдухалил Абдуганиевич, Разаков Азамат Жураевич · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-09-12
The article highlights the main etiological factors of congenital sensorineural hearing loss in children and its diagnostic significance in modern otorhinolaryngology. Sensorineural hearing loss at an early age creates…
Рахматуллаева Гулнара Кутпитдиновна, Кадырова Азиза Шавкатовна · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-09-12
Objective. To evaluate the prognostic significance of genetic markers of thrombophilia in the development of ischemic stroke in women, taking into account age stratification.Materials and Methods. A total of 97 women…
Маджидова Ёкутхон Набиевна, Рахмонов Исломбек Абдурашид угли, Азимова Нодира Мирваситовна · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-09-12
Male infertility is a multifaceted problem that can be caused by various etiopathogenetic factors. Among the most significant causes of infertility are infections and andrological diseases. Infectious diseases of the…