Correction of mitochondrial membrane state by glycyrrhetic acid derivatives in liver pathology in In vivo experiments

Чулиев, Икром Неъматуллаевич, Асраров, Музаффар Исламович, Мейлиева, Озада Келдияровна

Қўқон ДПИ. Илмий хабарлар · 2026-yil

Annotatsiya

In the article, the effect of new synthetic derivatives of glycyrrhetic acid on the functional parameters of mitochondria, as well as the parameters of the CsA- sensitive pore of mitochondrial membranes, were studied. It is shown for the first time that derivatives of glycyrrhetic acid - 2-(N-cytisine)-ethyl-3-0-acetyl-18bH-glycyrrhetate, 2-(N- cytisine)-isopropyl-3-0-acetyl-18bH-glycyrrhetate and N-(2-pyridyl)-3-0-acetyl-11- ketoolean-12-en-30-amide inhibit the activity of the CsA-sensitive pore and have a protective effect on mitochondrial membranes.

Maqola ma’lumotlari
MualliflarЧулиев, Икром Неъматуллаевич, Асраров, Музаффар Исламович, Мейлиева, Озада Келдияровна
JurnalҚўқон ДПИ. Илмий хабарлар
NashriyotҚўқон давлат педагогика институти
ISSN3030-3958
Nashr sanasi2026-08-10
Jild8
Son07
Betlar553-565
TilIngliz
DOI10.70728/a.series.tab.v08.i07.074
Indeksga qo‘shilgan2026-08-27

DOI: 10.70728/a.series.tab.v08.i07.074 · Maqolaning asl sahifasi

Kalit so‘zlar

mitochondria, membrane permeability, CsA-sensitive pore, lipid peroxidation, oxidative phosphorylation, antioxidants, prooxidants, free radicals, apoptosis, necrosis, glycyrrhetic acid derivatives.

Iqtibos keltirish

APAЧулиев, Икром Неъматуллаевич, Асраров, Музаффар Исламович, & Мейлиева, Озада Келдияровна (2026). CORRECTION OF MITOCHONDRIAL MEMBRANE STATE BY GLYCYRRHETIC ACID DERIVATIVES IN LIVER PATHOLOGY IN In vivo EXPERIMENTS. Қўқон ДПИ. Илмий хабарлар, 8(07), 553-565. https://doi.org/10.70728/a.series.tab.v08.i07.074
GOST (OAK)Чулиев, Икром Неъматуллаевич, Асраров, Музаффар Исламович, Мейлиева, Озада Келдияровна CORRECTION OF MITOCHONDRIAL MEMBRANE STATE BY GLYCYRRHETIC ACID DERIVATIVES IN LIVER PATHOLOGY IN In vivo EXPERIMENTS // Қўқон ДПИ. Илмий хабарлар. – 2026. – T. 8, № 07. – P. 553-565. – DOI: 10.70728/a.series.tab.v08.i07.074.
MLAЧулиев, Икром Неъматуллаевич, Асраров, Музаффар Исламович, and Мейлиева, Озада Келдияровна. “CORRECTION OF MITOCHONDRIAL MEMBRANE STATE BY GLYCYRRHETIC ACID DERIVATIVES IN LIVER PATHOLOGY IN In vivo EXPERIMENTS.” Қўқон ДПИ. Илмий хабарлар, 8(07), 553-565, 2026. https://doi.org/10.70728/a.series.tab.v08.i07.074
ChicagoЧулиев, Икром Неъматуллаевич, Асраров, Музаффар Исламович, and Мейлиева, Озада Келдияровна. “CORRECTION OF MITOCHONDRIAL MEMBRANE STATE BY GLYCYRRHETIC ACID DERIVATIVES IN LIVER PATHOLOGY IN In vivo EXPERIMENTS.” Қўқон ДПИ. Илмий хабарлар, 8(07), 553-565 (2026). https://doi.org/10.70728/a.series.tab.v08.i07.074
HarvardЧулиев, Икром Неъматуллаевич, Асраров, Музаффар Исламович, and Мейлиева, Озада Келдияровна (2026) ‘CORRECTION OF MITOCHONDRIAL MEMBRANE STATE BY GLYCYRRHETIC ACID DERIVATIVES IN LIVER PATHOLOGY IN In vivo EXPERIMENTS’, Қўқон ДПИ. Илмий хабарлар, 8(07), 553-565. https://doi.org/10.70728/a.series.tab.v08.i07.074
BibTeX
@article{article2026,
  title = {CORRECTION OF MITOCHONDRIAL MEMBRANE STATE BY GLYCYRRHETIC ACID DERIVATIVES IN LIVER PATHOLOGY IN In vivo EXPERIMENTS},
  author = {Чулиев, Икром Неъматуллаевич and Асраров, Музаффар Исламович and Мейлиева, Озада Келдияровна},
  journal = {Қўқон ДПИ. Илмий хабарлар},
  year = {2026},
  volume = {8},
  number = {07},
  pages = {553-565},
  doi = {10.70728/a.series.tab.v08.i07.074},
  url = {https://doi.org/10.70728/a.series.tab.v08.i07.074}
}

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