Influence of antioxidant system markers in rat brain tissue on cognitive functions

Tukhtaeva S.A., Tursunov D.Kh.

Ёш олимлар тиббиёт журнали · 2024-yil

Annotatsiya

Research dedicated to study the effect of nerve growth factor (NGF) on the parameters of the antioxidant system in the rat brain. From the submandibular salivary glands of male mice, we isolated and purified fractions with nerve growth activity. We study the effect of NGF on the parameters of the antioxidant system – catalase, superoxide dismutase (SOD), and malon dialdehyde (MDA). It was found that the activity of catalase increases at a concentration of NGF of 5 μg, with a further growth of concentration of NGF a decrease in the activity of the enzyme was observed. SOD activity tends to increase at NGF concentrations of 5 and 25 μg. The decrease in the content of MDA is pronounced with the introduction of various concentrations of NGF. Thus, the activity of antioxidant enzymes tends to be restored in the presence of NGF. Neuroprotectors can exhibit therapeutic efficacy of antioxidants in neurodegenerative diseases and ischemic brain damage.

Maqola ma’lumotlari
MualliflarTukhtaeva S.A., Tursunov D.Kh.
JurnalЁш олимлар тиббиёт журнали
NashriyotТошкент тиббиёт академияси
ISSN2181-3485
Nashr sanasi2024-12-09
Son12
Betlar102-106
TilIngliz
Ilmiy sohaTibbiyot
Indeksga qo‘shilgan2026-08-27

Maqolaning asl sahifasi

Kalit so‘zlar

nerve growth factor, cerebral cortex, antioxidant defense enzymes.

Ilmiy soha

Tibbiyot

Iqtibos keltirish

APATukhtaeva S.A., Tursunov D.Kh. (2024). INFLUENCE OF ANTIOXIDANT SYSTEM MARKERS IN RAT BRAIN TISSUE ON COGNITIVE FUNCTIONS. Ёш олимлар тиббиёт журнали, (12), 102-106. https://journals.tnmu.uz/index.php/yotj/article/view/869
GOST (OAK)Tukhtaeva S.A., Tursunov D.Kh. INFLUENCE OF ANTIOXIDANT SYSTEM MARKERS IN RAT BRAIN TISSUE ON COGNITIVE FUNCTIONS // Ёш олимлар тиббиёт журнали. – 2024. – № 12. – P. 102-106.
MLATukhtaeva S.A., Tursunov D.Kh. “INFLUENCE OF ANTIOXIDANT SYSTEM MARKERS IN RAT BRAIN TISSUE ON COGNITIVE FUNCTIONS.” Ёш олимлар тиббиёт журнали, (12), 102-106, 2024. https://journals.tnmu.uz/index.php/yotj/article/view/869
ChicagoTukhtaeva S.A., Tursunov D.Kh. “INFLUENCE OF ANTIOXIDANT SYSTEM MARKERS IN RAT BRAIN TISSUE ON COGNITIVE FUNCTIONS.” Ёш олимлар тиббиёт журнали, (12), 102-106 (2024). https://journals.tnmu.uz/index.php/yotj/article/view/869
HarvardTukhtaeva S.A., Tursunov D.Kh (2024) ‘INFLUENCE OF ANTIOXIDANT SYSTEM MARKERS IN RAT BRAIN TISSUE ON COGNITIVE FUNCTIONS’, Ёш олимлар тиббиёт журнали, (12), 102-106. https://journals.tnmu.uz/index.php/yotj/article/view/869
BibTeX
@article{tukhtaevasatursunovdkh2024,
  title = {INFLUENCE OF ANTIOXIDANT SYSTEM MARKERS IN RAT BRAIN TISSUE ON COGNITIVE FUNCTIONS},
  author = {Tukhtaeva S.A., Tursunov D.Kh.},
  journal = {Ёш олимлар тиббиёт журнали},
  year = {2024},
  number = {12},
  pages = {102-106},
  url = {https://journals.tnmu.uz/index.php/yotj/article/view/869}
}

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