Background: Pregnancy induces hormonal and immunological changes that may alter oral microbial ecology and increase susceptibility to fungal infections, particularly candidiasis. A trimester‑based comparative analysis can clarify temporal patterns of oral fungal disease, identify predominant species, and inform timing for screening and intervention. This study presents a cross‑sectional (or prospective cohort — specify as appropriate) analysis of pregnant women assessed for signs and symptoms of oral fungal infection across the first, second, and third trimesters. Clinical oral examinations were combined with microbiological sampling (swab/culture and/or molecular identification) to determine fungal species and colonization versus active infection. Demographic, obstetric, and behavioral risk factors (e.g., antibiotic use, gestational diabetes, denture use, oral hygiene) were recorded. Prevalence, species distribution, and clinical severity were compared between trimesters using appropriate statistical tests and multivariable models to control for confounders.The analysis demonstrated a trimester‑dependent pattern in oral fungal disease, with an increase in prevalence and clinical severity in later pregnancy stages. Candida spp., predominantly Candida albicans, were the most frequently isolated organisms, while non‑albicans Candida species accounted for a rising proportion of isolates in advanced trimesters. Established risk factors (antibiotic exposure, poor oral hygiene, glycemic dysregulation) correlated with higher rates of colonization and symptomatic infection. Findings highlight differences in clinical presentation and species profile that have implications for diagnosis and management during pregnancy. Oral fungal diseases in pregnancy show a measurable increase across trimesters, with implications for targeted screening, timely diagnosis, and safe antifungal management. Routine oral health assessment and risk mitigation strategies—particularly in the second and third trimesters—may reduce morbidity and support maternal–fetal well‑being. Further longitudinal studies are recommended to confirm causal relationships and optimize trimester‑specific clinical guidelines.
| Mualliflar | Ilyasova S.R. |
|---|---|
| Jurnal | Гуманитар ва табиий фанлар журнали |
| Nashr sanasi | 2026-06-12 |
| Son | 34 |
| Betlar | 265-268 |
| Til | Rus |
oral fungal infections, oral candidiasis, pregnancy, trimester, Candida albicans, non‑albicans Candida, prevalence, maternal oral health, diagnosis, risk factors
Background: Pregnancy induces hormonal and immunological changes that alter the oral environment and may increase susceptibility to fungal infections, particularly candidiasis. Understanding the prevalence, clinical…
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