BIOMATERIALS AND THEIR BIOLOGICAL COMPATIBILITY: A CLINICAL ANALYSIS OF PMMA, THERMOPLASTICS, BIOACTIVE POLYMERS, NANOMATERIALS, AND NEXT-GENERATION ZIRCONIA

Shovkatov O.Sh., Sharipov S.S., Akhundjanov R.A.

Гуманитар ва табиий фанлар журнали · 2025-yil

Annotatsiya

In recent years, the advancement of biomaterials in prosthodontics has led to notable improvements in biological compatibility, esthetic outcomes, and clinical performance. This prospective clinical study aimed to compare the biological integration, masticatory efficiency, patient satisfaction, and long-term stability of four groups of prosthodontic materials: conventional polymethyl methacrylate (PMMA), thermoplastic polyamides, bioactive polymers with nanofillers, and next-generation zirconia and composite blocks. A total of 120 edentulous patients were observed over a 24-month period. Results indicated that bioactive polymers and zirconia-based materials showed significantly superior gingival integration, chewing function, and esthetic stability compared to PMMA and thermoplastics (p < 0.05). Patient satisfaction was highest in the zirconia and bioactive groups (Likert score: 4.6–4.8), while PMMA showed the most complications, including discoloration and microfractures. These findings support the clinical transition toward bioactive nanocomposites and zirconia blocks as primary materials in modern prosthodontics, especially when integrated with CAD/CAM and 3D-printing technologies.

Maqola ma’lumotlari
MualliflarShovkatov O.Sh., Sharipov S.S., Akhundjanov R.A.
JurnalГуманитар ва табиий фанлар журнали
Nashr sanasi2025-12-10
Son28
Betlar19-25
TilRus

Kalit so‘zlar

Biomaterials, Prosthodontics, PMMA, Zirconia, Bioactive Polymers, Nanomaterials, Dentures, CAD/CAM, Clinical Performance.

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