This publication discusses the adverse effects of antiepileptic drugs on bone tissue, which increase the risk of fractures in patients with epilepsy compared with the general population. Many studies have shown a decrease in bone mineral density, an increase in the risk of osteopenia and osteoporosis in patients receiving traditional and new AEDs. Polytherapy and duration of AED use are associated with the most significant risk of decreased bone mineral density. Nevertheless, the molecular mechanisms of the effect of various AEDs on bone tissue remain poorly understood.
| Mualliflar | Муратов Фахмитдин Хайритдинович, Юсупова Дилноза Юсупжон қизи |
|---|---|
| Jurnal | Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research |
| Nashr sanasi | 2023-05-01 |
| Jild | 4 |
| Son | 2 |
| Til | Ingliz |
Эпилепсия, противоэпилептический препарат, дефицит витамина D, минеральная плотность костей, Epilepsy, antiepileptic drug, vitamin D deficiency, bone mineral density, Эпилепсия, антиепилептик препарат, Д витамини етишмовчилиги, суяк минерал зичлиги
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