Adherence to drug therapy in patients after acute myocardial infarction: a systematic review of the literature

Sokhibov, Dilshod, Trigulova, Raisa, Mirakhmedova, Nilufar, Сохибов, Дилшод, Тригулова, Р, Мирахмедова, Нилуфар, Soxibov, Dilshod, Trigulova, Raisa, Miraxmedova, Nilufar

O‘zbekiston кardiologiyasi · 2025-yil

Annotatsiya

Aim. To systematically analyze current approaches to assessing and improving medication adherence in patients after acute myocardial infarction during outpatient follow-up, with a particular focus on factors influencing treatment adherence and the role of a multidisciplinary approach. Materials and Methods. A systematic review of the literature on medication adherence after acute myocardial infarction was conducted. Data from large international studies were analyzed, including a meta-analysis of 10 studies involving 106,002 patients, the 2023 American Heart Association scientific statement, the 2023 ESC and 2025 ACC/AHA guidelines, and current cardiac rehabilitation programs. Results. A meta-analysis showed that good adherence to drug therapy is associated with reduced all-cause mortality (odds ratio 0.56; 95% CI: 0.45-0.69), cardiovascular mortality (OR 0.66; 95% CI: 0.51-0.87), and hospitalization rates (OR 0.61; 95% CI: 0.45-0.82). Non-adherence to therapy occurs in 30% of patients after myocardial infarction. Shared decision making, structured cardiac rehabilitation programs, and the involvement of multidisciplinary teams significantly improve long-term treatment adherence. Conclusion. Adherence to drug therapy is a key factor in improving the prognosis of patients after acute myocardial infarction. A multidisciplinary approach, including shared decision making, patient education, pharmaceutical counseling, and the use of digital technologies, demonstrates the greatest effectiveness in improving adherence.

Maqola ma’lumotlari
MualliflarSokhibov, Dilshod, Trigulova, Raisa, Mirakhmedova, Nilufar, Сохибов, Дилшод, Тригулова, Р, Мирахмедова, Нилуфар, Soxibov, Dilshod, Trigulova, Raisa, Miraxmedova, Nilufar
JurnalO‘zbekiston кardiologiyasi
Nashr sanasi2025-12-12
Jild2
Son4
Betlar399-406
TilRus
DOI10.70626/cardiouz-2025-2-00071

Kalit so‘zlar

acute myocardial infarction, adherence to therapy, outpatient monitoring, cardiac rehabilitation, shared decision making, острый инфаркт миокарда, приверженность терапии, амбулаторное наблюдение, кардиологическая реабилитация, совместное принятие решений, o'tkir miokard infarkti, terapiyaga rioya qilish, ambulatoriya monitoringi, yurak reabilitatsiyasi, birgalikda qaror qabul qilish

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