Cardioprotective approaches when prescribing iSGLT-2

Тригулова , Р, Мухтарова, Ш, Насырова , Х, Mukhtarova, SHakhnoza, Trigulova, Raisa, Nasirova , Khurshida, Mukhtarova, SHakhnoza, Trigulova, Raisa, Nasirova , Xurshida

O‘zbekiston кardiologiyasi · 2024-yil

Annotatsiya

Background. Sodium-Glucose Cotransporter-2 (NGLT-2) inhibitors have gained significant attention for their cardioprotective properties. This review explores the cardiovascular benefits of NGLT-2 inhibitors, particularly their impact on heart health in patients with comorbidities such as type 2 diabetes and heart failure. The primary objective is to evaluate the mechanisms and effectiveness of these inhibitors in improving cardiovascular outcomes. Methods. A comprehensive review of relevant literature was conducted, focusing on recent studies, including clinical trials and meta-analyses, to assess the impact of NGLT-2 inhibitors on heart failure, diabetes, and associated cardiovascular events. The review examines various approaches related to the use of NGLT-2 inhibitors in treating cardiovascular conditions. Key Content and Findings. NGLT-2 inhibitors have been shown to significantly reduce the risk of cardiovascular events, including heart failure hospitalizations and mortality. Their mechanisms of action include improving glucose control, reducing kidney burden, and mitigating endothelial dysfunction. The review highlights these mechanisms and the clinical benefits in treating patients with heart failure and type 2 diabetes. Conclusion. NGLT-2 inhibitors represent a valuable treatment option for improving heart health in patients with type 2 diabetes and heart failure. Further research is needed to optimize their use and fully understand their underlying mechanisms.

Maqola ma’lumotlari
MualliflarТригулова , Р, Мухтарова, Ш, Насырова , Х, Mukhtarova, SHakhnoza, Trigulova, Raisa, Nasirova , Khurshida, Mukhtarova, SHakhnoza, Trigulova, Raisa, Nasirova , Xurshida
JurnalO‘zbekiston кardiologiyasi
NashriyotЎзбекистон кардиологлар ассоциацияси
ISSN3060-4850
Nashr sanasi2024-03-30
Jild1
Son1
Betlar77-82
TilIngliz
Ilmiy sohaTibbiyot
DOI10.70626/cardiouz-2024-1-00010
Indeksga qo‘shilgan2026-08-26

DOI: 10.70626/cardiouz-2024-1-00010 · Maqolaning asl sahifasi

Kalit so‘zlar

NGLT-2 inhibitors, cardioprotection, heart failure, type 2 diabetes, cardiovascular risk, metabolic modulation, heart function, anti-inflammatory effects, ингибиторы НГЛТ-2, кардиопротекция, сердечная недостаточность, диабет 2 типа, кардиоваскулярный риск, метаболическая модуляция, функция сердца, противовоспа- лительные эффекты, NGLT-2 ingibitorlari, kardioprotektsiya, yurak yetishmovchiligi, 2-tur diabet, yurak-qon tomir xavfi, metabolik modulyatsiya, yurak funksiyasi, yallig‘lanishga qarshi ta’sirlar

Ilmiy soha

Tibbiyot

Iqtibos keltirish

APAТригулова , Р, Мухтарова, Ш, Насырова , Х, Mukhtarova, SHakhnoza, Trigulova, Raisa, Nasirova , Khurshida, Mukhtarova, SHakhnoza, Trigulova, Raisa, & Nasirova , Xurshida (2024). Cardioprotective approaches when prescribing iSGLT-2. O‘zbekiston кardiologiyasi, 1(1), 77-82. https://doi.org/10.70626/cardiouz-2024-1-00010
GOST (OAK)Тригулова , Р va b. Cardioprotective approaches when prescribing iSGLT-2 // O‘zbekiston кardiologiyasi. – 2024. – T. 1, № 1. – P. 77-82. – DOI: 10.70626/cardiouz-2024-1-00010.
MLAТригулова , Р, Мухтарова, Ш, Насырова , Х, Mukhtarova, SHakhnoza, Trigulova, Raisa, Nasirova , Khurshida, Mukhtarova, SHakhnoza, Trigulova, Raisa, and Nasirova , Xurshida. “Cardioprotective approaches when prescribing iSGLT-2.” O‘zbekiston кardiologiyasi, 1(1), 77-82, 2024. https://doi.org/10.70626/cardiouz-2024-1-00010
ChicagoТригулова , Р, Мухтарова, Ш, Насырова , Х, Mukhtarova, SHakhnoza, Trigulova, Raisa, Nasirova , Khurshida, Mukhtarova, SHakhnoza, Trigulova, Raisa, and Nasirova , Xurshida. “Cardioprotective approaches when prescribing iSGLT-2.” O‘zbekiston кardiologiyasi, 1(1), 77-82 (2024). https://doi.org/10.70626/cardiouz-2024-1-00010
HarvardТригулова , Р, Мухтарова, Ш, Насырова , Х, Mukhtarova, SHakhnoza, Trigulova, Raisa, Nasirova , Khurshida, Mukhtarova, SHakhnoza, Trigulova, Raisa, and Nasirova , Xurshida (2024) ‘Cardioprotective approaches when prescribing iSGLT-2’, O‘zbekiston кardiologiyasi, 1(1), 77-82. https://doi.org/10.70626/cardiouz-2024-1-00010
BibTeX
@article{article2024,
  title = {Cardioprotective approaches when prescribing iSGLT-2},
  author = {Тригулова , Р and Мухтарова, Ш and Насырова , Х and Mukhtarova, SHakhnoza and Trigulova, Raisa and Nasirova , Khurshida and Mukhtarova, SHakhnoza and Trigulova, Raisa and Nasirova , Xurshida},
  journal = {O‘zbekiston кardiologiyasi},
  year = {2024},
  volume = {1},
  number = {1},
  pages = {77-82},
  doi = {10.70626/cardiouz-2024-1-00010},
  url = {https://doi.org/10.70626/cardiouz-2024-1-00010}
}

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