Clinical, laboratory and molecular-genetic markers of the progression of non-alcoholic fatty liver disease (literature review and own data)

Хamrayev , A.A., Yuldasheva , D.H, Хамраев , А.А., Юлдашева , Д.Х, Хамраев , А.А., Yo'ldoshea , D.H

Жамият ва инновациялар / Общество и инновации / Society and innovations · 2021-yil

Annotatsiya

Non-alcoholic fatty liver disease (NAFLD) is one of the most common diseases in hepatology. First of all, this is associated with a high risk of progression of NAFLD with the development of non-alcoholic steatohepatitis (NASH), liver failure, and hepatocellular carcinoma. Epidemiological and genetic studies have shown the relationship between the morphological stage of NAFLD and hereditary factors. The article provides a review of the literature on the cytokines, MBOAT7 and GCKR genes. Also, a variant of the MBOAT7 and GCKR gene is associated with a high risk of fibrosis in patients with NAFLD and elevated serum triglyceride levels.

Maqola ma’lumotlari
MualliflarХamrayev , A.A., Yuldasheva , D.H, Хамраев , А.А., Юлдашева , Д.Х, Хамраев , А.А., Yo'ldoshea , D.H
JurnalЖамият ва инновациялар / Общество и инновации / Society and innovations
Nashr sanasi2021-04-05
Jild2
Son2/S
Betlar399-406
TilIngliz
DOI10.47689/2181-1415-vol2-iss2/s-pp399-406

Kalit so‘zlar

неалкогольная жировая болезнь печени, неалкогольный стеатогепатит, цитокины, ген MBOAT7, ген GCKR, цирроз, липиды, ожирение, cytokines, MBOAT7 gene, cirrhosis, nonalcoholicsteatohepatitis, GCKR gene, lipids, obesity, alkogolsiz yog'li jigar kasalligi, alkogolsiz steatohepatit, sitokinlar, MBOAT7 geni, GCKR geni, siroz, lipidlar, semirish

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