A randomized controlled trial (n=110, 55 in main and control groups) was conducted. The main group received a comprehensive program (medications, physiotherapy, McKenzie kinesthetic therapy, psychological support), while the control group received standard therapy. Pain (VAS), functional status (ODI), quality of life (SF-36), psychoemotional status (HADS), muscle strength, and MRI dynamics of Modic changes (MC) were assessed. Results: After 6 months in the main group: Pain reduction by 68.7% (vs 43.7% in control; p<0.001); ODI improvement by 66.4% (vs 36.1%; p<0.001); Increase in physical and mental SF-36 components by 51.7% and 33.6% (vs 23.3% and 13.7%; p<0.001); Regression of MC (type I→II) in 32.7% of patients (vs 12.7%; p=0.012). Conclusion: Comprehensive rehabilitation significantly outperforms standard therapy, providing pronounced symptomatic improvement and pathogenetic impact on MC. Results confirm the feasibility of its implementation into practice.
| Mualliflar | MIRJURAYEV Elbek Mirshavkatovich, ADAMBAYEV Zufar Ibragimovich, SAMIYEV Asliddin Sayitovich, ERGASHEV G’ulom Bo’riyevich |
|---|---|
| Jurnal | Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali |
| Nashr sanasi | 2025-12-02 |
| Jild | 10 |
| Son | 5 |
| Til | Rus |
неспецифическая боль в спине, спондилодисцит по Модику, реабилитация, кинезиотерапия, нейромодуляция, рандомизированное исследование, качество жизни, non-specific back pain, Modic spondylodiscitis, rehabilitation, kinesthetic therapy, neuromodulation, randomized trial, quality of life, maxsus bo'lmagan orqa og'riq, Modik bo'yicha spondilodisitit, reabilitatsiya, kinezioterapiya, neyromodulyatsiya, randomizatsiya qilingan tadqiqot, hayot sifati
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