Effectiveness of prolonged antibiotic therapy in children with exudative otitis media

LUTFULLAEV Umrillo Lutfullaevich, KOBILOVA Shakhodat Shokirovna, MADAMINOVA Nigora Ergashovna, ZOIROV Otabek Toir ugli, BURONOV Farrukh Yakhshiboevich, MAKHAMOV Khusan Omonkul ugli

Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali · 2024-yil

Annotatsiya

Otitis media (OM) remains a significant health issue, particularly in Central Asia and Russia, where access to healthcare is limited. This study aimed to compare the effectiveness of long-term antibiotic therapy (amoxicillin) versus placebo in treating exudative otitis media (EOM) and assess the colonization by antibiotic-resistant pathogens. Conducted at Samarkand State Medical University, the study involved 100 children under 12 months old. Participants were randomized to receive either amoxicillin or placebo for up to 24 weeks. The primary outcome was the restoration of normal middle ear aeration, confirmed by tympanometry. Results showed fewer tympanic membrane perforations and a higher success rate in the amoxicillin group. Pathogen carriage was reduced in the antibiotic group without a significant increase in resistant strains. Prolonged antibiotic therapy may benefit high-risk children in regions with limited healthcare access.

Maqola ma’lumotlari
MualliflarLUTFULLAEV Umrillo Lutfullaevich, KOBILOVA Shakhodat Shokirovna, MADAMINOVA Nigora Ergashovna, ZOIROV Otabek Toir ugli, BURONOV Farrukh Yakhshiboevich, MAKHAMOV Khusan Omonkul ugli
JurnalJournal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali
NashriyotТошкент давлат стоматалогия институти, , «Expert Lawyers» MЧЖ
ISSN2181-9300
Nashr sanasi2024-12-24
Jild9
Son5
TilIngliz
Ilmiy sohaTibbiyot
Indeksga qo‘shilgan2026-08-27

Maqolaning asl sahifasi

Kalit so‘zlar

Средний отит, экссудативный отит, антибиотикотерапия, амоксициллин, колонизация патогенов, педиатрия, доступ к медицине, Otitis media, exudative otitis, antibiotic therapy, amoxicillin, pathogen colonization, pediatric, healthcare access

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Iqtibos keltirish

APALUTFULLAEV Umrillo Lutfullaevich, KOBILOVA Shakhodat Shokirovna, MADAMINOVA Nigora Ergashovna, ZOIROV Otabek Toir ugli, BURONOV Farrukh Yakhshiboevich, & MAKHAMOV Khusan Omonkul ugli (2024). EFFECTIVENESS OF PROLONGED ANTIBIOTIC THERAPY IN CHILDREN WITH EXUDATIVE OTITIS MEDIA. Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 9(5). https://tadqiqot.uz/index.php/biomedicine/article/view/10622
GOST (OAK)LUTFULLAEV Umrillo Lutfullaevich va b. EFFECTIVENESS OF PROLONGED ANTIBIOTIC THERAPY IN CHILDREN WITH EXUDATIVE OTITIS MEDIA // Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali. – 2024. – T. 9, № 5.
MLALUTFULLAEV Umrillo Lutfullaevich, KOBILOVA Shakhodat Shokirovna, MADAMINOVA Nigora Ergashovna, ZOIROV Otabek Toir ugli, BURONOV Farrukh Yakhshiboevich, and MAKHAMOV Khusan Omonkul ugli. “EFFECTIVENESS OF PROLONGED ANTIBIOTIC THERAPY IN CHILDREN WITH EXUDATIVE OTITIS MEDIA.” Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 9(5), 2024. https://tadqiqot.uz/index.php/biomedicine/article/view/10622
ChicagoLUTFULLAEV Umrillo Lutfullaevich, KOBILOVA Shakhodat Shokirovna, MADAMINOVA Nigora Ergashovna, ZOIROV Otabek Toir ugli, BURONOV Farrukh Yakhshiboevich, and MAKHAMOV Khusan Omonkul ugli. “EFFECTIVENESS OF PROLONGED ANTIBIOTIC THERAPY IN CHILDREN WITH EXUDATIVE OTITIS MEDIA.” Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 9(5) (2024). https://tadqiqot.uz/index.php/biomedicine/article/view/10622
HarvardLUTFULLAEV Umrillo Lutfullaevich, KOBILOVA Shakhodat Shokirovna, MADAMINOVA Nigora Ergashovna, ZOIROV Otabek Toir ugli, BURONOV Farrukh Yakhshiboevich, and MAKHAMOV Khusan Omonkul ugli (2024) ‘EFFECTIVENESS OF PROLONGED ANTIBIOTIC THERAPY IN CHILDREN WITH EXUDATIVE OTITIS MEDIA’, Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 9(5). https://tadqiqot.uz/index.php/biomedicine/article/view/10622
BibTeX
@article{lutfullaevumrillolutfullaevich2024,
  title = {EFFECTIVENESS OF PROLONGED ANTIBIOTIC THERAPY IN CHILDREN WITH EXUDATIVE OTITIS MEDIA},
  author = {LUTFULLAEV Umrillo Lutfullaevich and KOBILOVA Shakhodat Shokirovna and MADAMINOVA Nigora Ergashovna and ZOIROV Otabek Toir ugli and BURONOV Farrukh Yakhshiboevich and MAKHAMOV Khusan Omonkul ugli},
  journal = {Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali},
  year = {2024},
  volume = {9},
  number = {5},
  url = {https://tadqiqot.uz/index.php/biomedicine/article/view/10622}
}

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