Microbiological factors in the development of chronic periodontitis and their pathogenetic significance

Pardayev, Anvar, Toshtemirova, Ozoda

Жанубий оролбўйи тиббиёт журнали · 2026-yil

Annotatsiya

This article examines the role of microbiological factors in the development of chronic periodontitis and their pathogenetic significance. Chronic periodontitis is a multifactorial inflammatory disease of periodontal tissues characterized by progressive destruction of connective tissue attachment and alveolar bone, eventually leading to tooth loss. While systemic and local risk factors such as immune status, metabolic disorders, and poor oral hygiene play essential roles, the microbiological component remains central to its initiation and progression. The paper highlights the complex interactions between periodontal pathogens, host immune responses, and biofilm formation. Comparative data from both classical and modern studies illustrate the transition of periodontal microbiota from commensal to pathogenic states. The analysis emphasizes the pathogenic mechanisms of Porphyromonas gingivalis, Aggregatibacter actinomycetemcomitans, and Tannerella forsythia, and their synergistic interactions with other microorganisms. The results underscore the importance of early microbiological diagnosis, targeted antimicrobial therapy, and host modulation strategies in the management of chronic periodontitis.

Maqola ma’lumotlari
MualliflarPardayev, Anvar, Toshtemirova, Ozoda
JurnalЖанубий оролбўйи тиббиёт журнали
NashriyotТТА Урганч филиали
ISSN3093-8740, 2012-2021
Nashr sanasi2026-06-03
Jild2
Son2
Betlar223-227
TilIngliz
Ilmiy sohaTibbiyot
Indeksga qo‘shilgan2026-08-26

Maqolaning asl sahifasi

Kalit so‘zlar

Chronic periodontitis, microbiological factors, pathogenicity, periodontal pathogens, biofilm

Ilmiy soha

Tibbiyot

Iqtibos keltirish

APAPardayev, Anvar, & Toshtemirova, Ozoda (2026). MICROBIOLOGICAL FACTORS IN THE DEVELOPMENT OF CHRONIC PERIODONTITIS AND THEIR PATHOGENETIC SIGNIFICANCE. Жанубий оролбўйи тиббиёт журнали, 2(2), 223-227. http://journal.urdti.uz/index/article/view/618
GOST (OAK)Pardayev, Anvar, Toshtemirova, Ozoda MICROBIOLOGICAL FACTORS IN THE DEVELOPMENT OF CHRONIC PERIODONTITIS AND THEIR PATHOGENETIC SIGNIFICANCE // Жанубий оролбўйи тиббиёт журнали. – 2026. – T. 2, № 2. – P. 223-227.
MLAPardayev, Anvar, and Toshtemirova, Ozoda. “MICROBIOLOGICAL FACTORS IN THE DEVELOPMENT OF CHRONIC PERIODONTITIS AND THEIR PATHOGENETIC SIGNIFICANCE.” Жанубий оролбўйи тиббиёт журнали, 2(2), 223-227, 2026. http://journal.urdti.uz/index/article/view/618
ChicagoPardayev, Anvar, and Toshtemirova, Ozoda. “MICROBIOLOGICAL FACTORS IN THE DEVELOPMENT OF CHRONIC PERIODONTITIS AND THEIR PATHOGENETIC SIGNIFICANCE.” Жанубий оролбўйи тиббиёт журнали, 2(2), 223-227 (2026). http://journal.urdti.uz/index/article/view/618
HarvardPardayev, Anvar, and Toshtemirova, Ozoda (2026) ‘MICROBIOLOGICAL FACTORS IN THE DEVELOPMENT OF CHRONIC PERIODONTITIS AND THEIR PATHOGENETIC SIGNIFICANCE’, Жанубий оролбўйи тиббиёт журнали, 2(2), 223-227. http://journal.urdti.uz/index/article/view/618
BibTeX
@article{pardayevanvar2026,
  title = {MICROBIOLOGICAL FACTORS IN THE DEVELOPMENT OF CHRONIC PERIODONTITIS AND THEIR PATHOGENETIC SIGNIFICANCE},
  author = {Pardayev, Anvar and Toshtemirova, Ozoda},
  journal = {Жанубий оролбўйи тиббиёт журнали},
  year = {2026},
  volume = {2},
  number = {2},
  pages = {223-227},
  url = {http://journal.urdti.uz/index/article/view/618}
}

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