F-27 изохинолин алкалоидининг миокард қисқариши фаоллигига таъсир механизмини тавсифлаш Ш.Б.Қурбонова –тадқиқотчи

Жумаев, И.З., Бобоев, С.Н., Усманов, П.Б., Есимбетов, А.Т., Жўрақулов, Ш.Н.

Ilim ha’m ja’miyet · 2022-yil

Annotatsiya

To date, the search for new pharmacological methods for the prevention and treatment of diseases of the cardiovascular system is one of the urgent problems of modern pharmacology and medicine. Of particular interest is the fact that isoquinoline alkaloids currently have a pronounced antiarrhythmic effect. In our studies, it was found that the isoquinoline alkaloid F-27 has a negative inotropic effect on the contractile activity of the papillary muscle of the rat heart. It has been proven that the negative inotropic effect of this alkaloid is partly due to the blockade of Ca2+-channels. Experiments with lidocaine show that the negative inotropic effect of the F-27 alkaloid is mainly due to the blocking of Na+-channels.

Maqola ma’lumotlari
MualliflarЖумаев, И.З., Бобоев, С.Н., Усманов, П.Б., Есимбетов, А.Т., Жўрақулов, Ш.Н.
JurnalIlim ha’m ja’miyet
NashriyotНукус давлат педагогика институти
ISSN2010-720x, 2181-1555
Nashr sanasi2022-10-11
Son4-1
Betlar22-25
TilO‘zbek
Indeksga qo‘shilgan2026-08-26

Maqolaning asl sahifasi

Kalit so‘zlar

изохинолин, кардиомиоцит, папилляр мускул, ион канал, isoquinoline, cardiomyocyte, papillary muscle, ion channel

Iqtibos keltirish

APAЖумаев, И.З., Бобоев, С.Н., Усманов, П.Б., Есимбетов, А.Т., & Жўрақулов, Ш.Н. (2022). F-27 ИЗОХИНОЛИН АЛКАЛОИДИНИНГ МИОКАРД ҚИСҚАРИШИ ФАОЛЛИГИГА ТАЪСИР МЕХАНИЗМИНИ ТАВСИФЛАШ Ш.Б.Қурбонова –тадқиқотчи. Ilim ha’m ja’miyet, (4-1), 22-25. https://journal.ndpi.uz/index/article/view/2022-4-1-010
GOST (OAK)Жумаев, И.З. va b. F-27 ИЗОХИНОЛИН АЛКАЛОИДИНИНГ МИОКАРД ҚИСҚАРИШИ ФАОЛЛИГИГА ТАЪСИР МЕХАНИЗМИНИ ТАВСИФЛАШ Ш.Б.Қурбонова –тадқиқотчи // Ilim ha’m ja’miyet. – 2022. – № 4-1. – B. 22-25.
MLAЖумаев, И.З., Бобоев, С.Н., Усманов, П.Б., Есимбетов, А.Т., and Жўрақулов, Ш.Н. “F-27 ИЗОХИНОЛИН АЛКАЛОИДИНИНГ МИОКАРД ҚИСҚАРИШИ ФАОЛЛИГИГА ТАЪСИР МЕХАНИЗМИНИ ТАВСИФЛАШ Ш.Б.Қурбонова –тадқиқотчи.” Ilim ha’m ja’miyet, (4-1), 22-25, 2022. https://journal.ndpi.uz/index/article/view/2022-4-1-010
ChicagoЖумаев, И.З., Бобоев, С.Н., Усманов, П.Б., Есимбетов, А.Т., and Жўрақулов, Ш.Н. “F-27 ИЗОХИНОЛИН АЛКАЛОИДИНИНГ МИОКАРД ҚИСҚАРИШИ ФАОЛЛИГИГА ТАЪСИР МЕХАНИЗМИНИ ТАВСИФЛАШ Ш.Б.Қурбонова –тадқиқотчи.” Ilim ha’m ja’miyet, (4-1), 22-25 (2022). https://journal.ndpi.uz/index/article/view/2022-4-1-010
HarvardЖумаев, И.З., Бобоев, С.Н., Усманов, П.Б., Есимбетов, А.Т., and Жўрақулов, Ш.Н (2022) ‘F-27 ИЗОХИНОЛИН АЛКАЛОИДИНИНГ МИОКАРД ҚИСҚАРИШИ ФАОЛЛИГИГА ТАЪСИР МЕХАНИЗМИНИ ТАВСИФЛАШ Ш.Б.Қурбонова –тадқиқотчи’, Ilim ha’m ja’miyet, (4-1), 22-25. https://journal.ndpi.uz/index/article/view/2022-4-1-010
BibTeX
@article{article2022,
  title = {F-27 ИЗОХИНОЛИН АЛКАЛОИДИНИНГ МИОКАРД ҚИСҚАРИШИ ФАОЛЛИГИГА ТАЪСИР МЕХАНИЗМИНИ ТАВСИФЛАШ Ш.Б.Қурбонова –тадқиқотчи},
  author = {Жумаев, И.З. and Бобоев, С.Н. and Усманов, П.Б. and Есимбетов, А.Т. and Жўрақулов, Ш.Н.},
  journal = {Ilim ha’m ja’miyet},
  year = {2022},
  number = {4-1},
  pages = {22-25},
  url = {https://journal.ndpi.uz/index/article/view/2022-4-1-010}
}

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