Immunological aspects in young children with congenital heart defects

TAIROVA Sakina Bahodirovna, MUXAMADIEVA Lola Atamuradovna

Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali · 2023-yil

Annotatsiya

Objective: to study the indicators of the immune status in children with septal congenital heart defects (CHD). Materials and мethods: Young children with septal CHD were prospectively recruited between 2021 and 2022. The survey included 138 infants with septal CHD, among which 73 (52.3%) boys and 65 (47.7%) girls. The concentration of immunoglobulins - Ig A, Ig M, Ig G in blood serum was determined by linked immunosorbent assay (LIA), and the determination of the pro-inflammatory cytokine interleukin-6 (IL-6) in blood serum was based on the sandwich LIA method. Results: The study of the concentrations of the main classes of immunoglobulins G, A and M showed a decrease in the synthesis of IgA in septal CHD in children - 0.17±0.01 g/l. Analysis of the cytokine status of sick children showed a slight increase in IL-6 titer. Conclusions. The presented results made it possible to identify the main immunological features in septal congenital heart disease in young children. Thus, the data obtained characterize the decrease in the body's reactivity against the background of circulatory disorders.

Maqola ma’lumotlari
MualliflarTAIROVA Sakina Bahodirovna, MUXAMADIEVA Lola Atamuradovna
JurnalJournal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali
NashriyotТошкент давлат стоматалогия институти, , «Expert Lawyers» MЧЖ
ISSN2181-9300
Nashr sanasi2023-11-01
Jild8
Son4
TilIngliz
Ilmiy sohaTibbiyot
Indeksga qo‘shilgan2026-08-27

Maqolaning asl sahifasi

Kalit so‘zlar

врожденный порок сердца, иммунный статус, дети, интерлейкин, иммуноглобулин, congenital heart disease, immune status, children, interleukin, immunoglobulin, tug'ma yurak nuqsoni, immun status, bolalar, interleykin, immunoglobulin

Ilmiy soha

Tibbiyot

Iqtibos keltirish

APATAIROVA Sakina Bahodirovna, & MUXAMADIEVA Lola Atamuradovna (2023). IMMUNOLOGICAL ASPECTS IN YOUNG CHILDREN WITH CONGENITAL HEART DEFECTS. Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 8(4). https://tadqiqot.uz/index.php/biomedicine/article/view/8260
GOST (OAK)TAIROVA Sakina Bahodirovna, MUXAMADIEVA Lola Atamuradovna IMMUNOLOGICAL ASPECTS IN YOUNG CHILDREN WITH CONGENITAL HEART DEFECTS // Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali. – 2023. – T. 8, № 4.
MLATAIROVA Sakina Bahodirovna, and MUXAMADIEVA Lola Atamuradovna. “IMMUNOLOGICAL ASPECTS IN YOUNG CHILDREN WITH CONGENITAL HEART DEFECTS.” Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 8(4), 2023. https://tadqiqot.uz/index.php/biomedicine/article/view/8260
ChicagoTAIROVA Sakina Bahodirovna, and MUXAMADIEVA Lola Atamuradovna. “IMMUNOLOGICAL ASPECTS IN YOUNG CHILDREN WITH CONGENITAL HEART DEFECTS.” Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 8(4) (2023). https://tadqiqot.uz/index.php/biomedicine/article/view/8260
HarvardTAIROVA Sakina Bahodirovna, and MUXAMADIEVA Lola Atamuradovna (2023) ‘IMMUNOLOGICAL ASPECTS IN YOUNG CHILDREN WITH CONGENITAL HEART DEFECTS’, Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 8(4). https://tadqiqot.uz/index.php/biomedicine/article/view/8260
BibTeX
@article{tairovasakinabahodirovna2023,
  title = {IMMUNOLOGICAL ASPECTS IN YOUNG CHILDREN WITH CONGENITAL HEART DEFECTS},
  author = {TAIROVA Sakina Bahodirovna and MUXAMADIEVA Lola Atamuradovna},
  journal = {Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali},
  year = {2023},
  volume = {8},
  number = {4},
  url = {https://tadqiqot.uz/index.php/biomedicine/article/view/8260}
}

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