Objective: To study morphometric changes in the structure of the liver of white rats with polypharmacy with anti-inflammatory drugs. Methods: The study was carried out on 50 male white rats, weighing from 210 to 320 g, kept in a vivarium with a standard diet, free access to water, and a normal lighting regime. The animals were divided into 3 groups. Results: When comparing the morphometric parameters of the rats of the 3rd group with those of the 2nd group, a significant decrease was found. The area of the hepatic cell decreased 5.14%, 5.05%, 3.19% and 3.02%, the outer diameter of the central vena decreased 8.13%, 6.11%, 4.08% and 3.42%, the diameter of the biliary duct decreased by 6.33%, 5.09%, 3.12% and 3.08%, the outer diameter of the arterial decreased by 7.12%, 5.07%, 5.03% and 4.48%, the diameter of the hepatic biliary duct decreased by 4.47%, 4.04%, 3.07% and 2.31%. Conclusions. The presence of the effect of polypharmacy by anti-inflammatory drugs on the liver indicates that polypharmacy has a detrimental effect on urinary excretion, reduces biliary excretion and has a sufficient level of risk for the body.
| Mualliflar | USANOV Sanjar Sadinovich, KORJAVOV Sherali Oblakulovich, KURBONOVA Latofat Murodullaevna |
|---|---|
| Jurnal | Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali |
| Nashriyot | Тошкент давлат стоматалогия институти, , «Expert Lawyers» MЧЖ |
| ISSN | 2181-9300 |
| Nashr sanasi | 2023-08-17 |
| Jild | 8 |
| Son | 3 |
| Til | Ingliz |
| Ilmiy soha | Tibbiyot |
| Indeksga qo‘shilgan | 2026-08-27 |
печень, паренхима, центральная вена, желчные протоки, полипрагмазия, liver, parenchimy, central vena, biliary duct, polypharmacy, jigar, parenxima, markaziy vena, o’t yo’llari, polipragmaziya
| APA | USANOV Sanjar Sadinovich, KORJAVOV Sherali Oblakulovich, & KURBONOVA Latofat Murodullaevna (2023). MORPHOLOGY AND MORPHOMETRIC CHARACTERISTICS OF LIVER TISSUE OF GROUP FOUR WHITE RATS. Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 8(3). https://tadqiqot.uz/index.php/biomedicine/article/view/7716 |
|---|---|
| GOST (OAK) | USANOV Sanjar Sadinovich, KORJAVOV Sherali Oblakulovich, KURBONOVA Latofat Murodullaevna MORPHOLOGY AND MORPHOMETRIC CHARACTERISTICS OF LIVER TISSUE OF GROUP FOUR WHITE RATS // Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali. – 2023. – T. 8, № 3. |
| MLA | USANOV Sanjar Sadinovich, KORJAVOV Sherali Oblakulovich, and KURBONOVA Latofat Murodullaevna. “MORPHOLOGY AND MORPHOMETRIC CHARACTERISTICS OF LIVER TISSUE OF GROUP FOUR WHITE RATS.” Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 8(3), 2023. https://tadqiqot.uz/index.php/biomedicine/article/view/7716 |
| Chicago | USANOV Sanjar Sadinovich, KORJAVOV Sherali Oblakulovich, and KURBONOVA Latofat Murodullaevna. “MORPHOLOGY AND MORPHOMETRIC CHARACTERISTICS OF LIVER TISSUE OF GROUP FOUR WHITE RATS.” Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 8(3) (2023). https://tadqiqot.uz/index.php/biomedicine/article/view/7716 |
| Harvard | USANOV Sanjar Sadinovich, KORJAVOV Sherali Oblakulovich, and KURBONOVA Latofat Murodullaevna (2023) ‘MORPHOLOGY AND MORPHOMETRIC CHARACTERISTICS OF LIVER TISSUE OF GROUP FOUR WHITE RATS’, Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 8(3). https://tadqiqot.uz/index.php/biomedicine/article/view/7716 |
| BibTeX | @article{usanovsanjarsadinovich2023,
title = {MORPHOLOGY AND MORPHOMETRIC CHARACTERISTICS OF LIVER TISSUE OF GROUP FOUR WHITE RATS},
author = {USANOV Sanjar Sadinovich and KORJAVOV Sherali Oblakulovich and KURBONOVA Latofat Murodullaevna},
journal = {Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali},
year = {2023},
volume = {8},
number = {3},
url = {https://tadqiqot.uz/index.php/biomedicine/article/view/7716}
} |
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