Morphology of apudocytes of the epithelium of the mucous membrane of the small intestine of rabbits of the post-reproductive period

ORIPOV Firdavs Sur'atovich, KHOLKHOZHAEV Farrukh Ikromovich, MAYUSUPOVA Bivifotima Mukhamatsobirzoda

Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali · 2023-yil

Annotatsiya

Actuality. Disruption of the absorption of substances (including calcium) necessary for the body during old age and old age due to derailment of local neurotrophic and endocrine management and control causes the development of certain diseases of the musculoskeletal system (osteopenia, osteoporosis, osteomalacia, etc.). One of the most common causes of osteoporosis is intestinal inflammation [1]. Purpose. Study of morphological and morphometric characteristics of endocrinocytes of the epithelium of the mucous membrane of the small intestine of post-reproductive age rabbits. Materials and methods. The small intestines of 12 rabbits of post-reproductive age, which have lost their ability to reproduce, were taken as material for our study. Animals were euthanized and slaughtered in accordance with bioethical guidelines, and the small intestine was collected in coils and fixed in Buen's fluid. Results. If in animals of the reproductive period in the epithelium of the wall of the small intestine, the number of endocrinocytes in the field of view of the microscope is on average from 6 to 9, then in rabbits of post-reproductive age this figure decreases to 4 and 5. At the same time, it can be observed that the number of open type endocrinocytes is also reduced. When we studied the structure of endocrinocytes containing fluorogenic amines, the above-described difference between animals of reproductive and post-reproductive age was confirmed. In the endocrinocytes of rabbits of post-reproductive age, the level of impregnation also decreases, as a result of which the shape of the cells changes to a certain extent. Vacuolization of the cytoplasm of endocrinocytes is often observed. Conclusion. The morphological and morphometric features of endocrinocytes of the small intestine of rabbits in the post-reproductive period were studied. In the wall of the small intestine of mature rabbits, endocrine cells of both open and closed types are found. In the epithelium of the villi of the small intestine, endocrinocytes of the open type are more common, and in the crypts of the closed type. In the post-reproduction period, the degree of impregnation in the endocrinocytes of the small intestine of rabbits decreases, as a result of which the shape of these cells also changes to some extent. In laboratory animals of post-reproduction age, there is a change in the local diffuse endocrine apparatus of the small intestine, which can lead to a violation of absorption processes. This, in turn, will cause a decrease in the concentration of calcium in the blood, therefore, a decrease in the degree of mineralization of bone tissue, which may be one of the reasons for the development of senile osteoporosis.

Maqola ma’lumotlari
MualliflarORIPOV Firdavs Sur'atovich, KHOLKHOZHAEV Farrukh Ikromovich, MAYUSUPOVA Bivifotima Mukhamatsobirzoda
JurnalJournal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali
NashriyotТошкент давлат стоматалогия институти, , «Expert Lawyers» MЧЖ
ISSN2181-9300
Nashr sanasi2023-04-27
Jild8
Son1
TilIngliz
Ilmiy sohaTibbiyot
Indeksga qo‘shilgan2026-08-27

Maqolaning asl sahifasi

Kalit so‘zlar

кролики, тонкая кишка, сенильный остеопороз, пострепродукционный период, диффузная эндокринная система, апудоцит, костная минерализация., rabbits, small intestine, senile osteoporosis, post-reproductive period, diffuse endocrine system, apudocyte, bone mineralization., қуёнлар, ингичка ичак, сенил остеопороз, пострепродукцион давр, диффуз эндокрин тизим, апудоцит, суяк минерализацияси

Ilmiy soha

Tibbiyot

Iqtibos keltirish

APAORIPOV Firdavs Sur'atovich, KHOLKHOZHAEV Farrukh Ikromovich, & MAYUSUPOVA Bivifotima Mukhamatsobirzoda (2023). MORPHOLOGY OF APUDOCYTES OF THE EPITHELIUM OF THE MUCOUS MEMBRANE OF THE SMALL INTESTINE OF RABBITS OF THE POST-REPRODUCTIVE PERIOD. Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 8(1). https://tadqiqot.uz/index.php/biomedicine/article/view/7062
GOST (OAK)ORIPOV Firdavs Sur'atovich, KHOLKHOZHAEV Farrukh Ikromovich, MAYUSUPOVA Bivifotima Mukhamatsobirzoda MORPHOLOGY OF APUDOCYTES OF THE EPITHELIUM OF THE MUCOUS MEMBRANE OF THE SMALL INTESTINE OF RABBITS OF THE POST-REPRODUCTIVE PERIOD // Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali. – 2023. – T. 8, № 1.
MLAORIPOV Firdavs Sur'atovich, KHOLKHOZHAEV Farrukh Ikromovich, and MAYUSUPOVA Bivifotima Mukhamatsobirzoda. “MORPHOLOGY OF APUDOCYTES OF THE EPITHELIUM OF THE MUCOUS MEMBRANE OF THE SMALL INTESTINE OF RABBITS OF THE POST-REPRODUCTIVE PERIOD.” Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 8(1), 2023. https://tadqiqot.uz/index.php/biomedicine/article/view/7062
ChicagoORIPOV Firdavs Sur'atovich, KHOLKHOZHAEV Farrukh Ikromovich, and MAYUSUPOVA Bivifotima Mukhamatsobirzoda. “MORPHOLOGY OF APUDOCYTES OF THE EPITHELIUM OF THE MUCOUS MEMBRANE OF THE SMALL INTESTINE OF RABBITS OF THE POST-REPRODUCTIVE PERIOD.” Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 8(1) (2023). https://tadqiqot.uz/index.php/biomedicine/article/view/7062
HarvardORIPOV Firdavs Sur'atovich, KHOLKHOZHAEV Farrukh Ikromovich, and MAYUSUPOVA Bivifotima Mukhamatsobirzoda (2023) ‘MORPHOLOGY OF APUDOCYTES OF THE EPITHELIUM OF THE MUCOUS MEMBRANE OF THE SMALL INTESTINE OF RABBITS OF THE POST-REPRODUCTIVE PERIOD’, Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 8(1). https://tadqiqot.uz/index.php/biomedicine/article/view/7062
BibTeX
@article{oripovfirdavssuratovich2023,
  title = {MORPHOLOGY OF APUDOCYTES OF THE EPITHELIUM OF THE MUCOUS MEMBRANE OF THE SMALL INTESTINE OF RABBITS OF THE POST-REPRODUCTIVE PERIOD},
  author = {ORIPOV Firdavs Sur'atovich and KHOLKHOZHAEV Farrukh Ikromovich and MAYUSUPOVA Bivifotima Mukhamatsobirzoda},
  journal = {Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali},
  year = {2023},
  volume = {8},
  number = {1},
  url = {https://tadqiqot.uz/index.php/biomedicine/article/view/7062}
}

Boshqa maqola uchun iqtibos tayyorlash

Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali jurnalidan boshqa maqolalar

Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali — barcha maqolalar · 2023-yil arxivi

ORIPOV Firdavs Sur'atovich — boshqa maqolalari

Tibbiyot sohasidagi boshqa maqolalar

Tibbiyot sohasidagi OAK jurnallari