The significance of disturbances in the regulation of endothelial functions in the development of exfolitive cheilitis

ABDUYUSUPOVA Kamola Mirvaliyevna, KHAIDAROV Artur Mikhailovich, KHADJIMETOV Abdugafur Akhadov

Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali · 2023-yil

Annotatsiya

Purpose: Evaluating the role of vascular endothelial cells in the development of exfoliative cheilitis. Methods: The research included 48 patients (comparison group) aged 16 to 65 years with a dry form of exfoliative cheilitis. The control group consisted of 20 healthy people. Results: Analysis of the results of the study showed a significant increase in vascular endothelial growth factor in the examined patients by an average of 57% when compared with the control group. Considering that VEGF is a stress-induced protein, its regulation is compared to other oxygen- and glucose-regulated proteins; therefore, an increase in its level can be considered an adaptive response to oxygen deficiency, which is associated with the activation of metabolic pathways regulated by proteins such as hypoxia-induced factor 1, which leads to an increase in the expression of pro-angiogenic factor VEGF and fibroblast growth factors. Conclusions. Thus, endothelial dysfunction plays one of the most important roles in the development of exfoliative cheilitis and, therefore, the search for methods for its correction will reduce the risk of vascular complications.

Maqola ma’lumotlari
MualliflarABDUYUSUPOVA Kamola Mirvaliyevna, KHAIDAROV Artur Mikhailovich, KHADJIMETOV Abdugafur Akhadov
JurnalJournal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali
NashriyotТошкент давлат стоматалогия институти, , «Expert Lawyers» MЧЖ
ISSN2181-9300
Nashr sanasi2023-02-07
Jild7
Son6
TilIngliz
Ilmiy sohaTibbiyot
Indeksga qo‘shilgan2026-08-27

Maqolaning asl sahifasi

Kalit so‘zlar

эксфолиативный хейлит, эндотелиальная дисфункция, тканевая гипоксия, гемоваскулярный гомеостаз, exfoliative cheilitis, endothelial dysfunction, tissue hypoxia, hemovascular homeostasis., eksfoliativ xeylit, endoteliy disfunkctiya, to’qima gipoksiyasi, gemovaskulyar gomeostaz.

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Iqtibos keltirish

APAABDUYUSUPOVA Kamola Mirvaliyevna, KHAIDAROV Artur Mikhailovich, & KHADJIMETOV Abdugafur Akhadov (2023). THE SIGNIFICANCE OF DISTURBANCES IN THE REGULATION OF ENDOTHELIAL FUNCTIONS IN THE DEVELOPMENT OF EXFOLITIVE CHEILITIS. Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 7(6). https://tadqiqot.uz/index.php/biomedicine/article/view/6760
GOST (OAK)ABDUYUSUPOVA Kamola Mirvaliyevna, KHAIDAROV Artur Mikhailovich, KHADJIMETOV Abdugafur Akhadov THE SIGNIFICANCE OF DISTURBANCES IN THE REGULATION OF ENDOTHELIAL FUNCTIONS IN THE DEVELOPMENT OF EXFOLITIVE CHEILITIS // Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali. – 2023. – T. 7, № 6.
MLAABDUYUSUPOVA Kamola Mirvaliyevna, KHAIDAROV Artur Mikhailovich, and KHADJIMETOV Abdugafur Akhadov. “THE SIGNIFICANCE OF DISTURBANCES IN THE REGULATION OF ENDOTHELIAL FUNCTIONS IN THE DEVELOPMENT OF EXFOLITIVE CHEILITIS.” Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 7(6), 2023. https://tadqiqot.uz/index.php/biomedicine/article/view/6760
ChicagoABDUYUSUPOVA Kamola Mirvaliyevna, KHAIDAROV Artur Mikhailovich, and KHADJIMETOV Abdugafur Akhadov. “THE SIGNIFICANCE OF DISTURBANCES IN THE REGULATION OF ENDOTHELIAL FUNCTIONS IN THE DEVELOPMENT OF EXFOLITIVE CHEILITIS.” Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 7(6) (2023). https://tadqiqot.uz/index.php/biomedicine/article/view/6760
HarvardABDUYUSUPOVA Kamola Mirvaliyevna, KHAIDAROV Artur Mikhailovich, and KHADJIMETOV Abdugafur Akhadov (2023) ‘THE SIGNIFICANCE OF DISTURBANCES IN THE REGULATION OF ENDOTHELIAL FUNCTIONS IN THE DEVELOPMENT OF EXFOLITIVE CHEILITIS’, Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 7(6). https://tadqiqot.uz/index.php/biomedicine/article/view/6760
BibTeX
@article{abduyusupovakamolamirvaliyevna2023,
  title = {THE SIGNIFICANCE OF DISTURBANCES IN THE REGULATION OF ENDOTHELIAL FUNCTIONS IN THE DEVELOPMENT OF EXFOLITIVE CHEILITIS},
  author = {ABDUYUSUPOVA Kamola Mirvaliyevna and KHAIDAROV Artur Mikhailovich and KHADJIMETOV Abdugafur Akhadov},
  journal = {Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali},
  year = {2023},
  volume = {7},
  number = {6},
  url = {https://tadqiqot.uz/index.php/biomedicine/article/view/6760}
}

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