EPIDEMIOLOGY OF OBSTRUCTIVE CHOLESTASIS IN CHILDREN

ALIYEV Mahmud Muslimovich, NEMATJONOV Farruh Zokirjon ogli, TUYCHIEV Golibjon Ormonovich, YULDASHEV Rustam Zafarjonovich

Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali · 2023-yil

Annotatsiya

Accurate data on the epidemiology of biliary obstruction have not been obtained. Obstructive cholestases in children of early age correspond to BA in 68-75% of points, and in 12-15% of points to cystic transformation of the liver common bile duct. In epidemiological data, the rate of biliary atresia is on average 1/15,000-18,000 worldwide, while according to Hanna Lampela's research, it is 1/17,000-1/19,000 among the European population. The incidence of common bile duct cystic transformation is 1 in 50,000 to 2,000,000 live births. Among the Asian population, BA has the highest rate of -1/9600 and found that the rate of biliary cystic transformation is 1:100,000. The prevalence of BA among the population of Africa and developing countries has not been fully studied until now. According to Aliev M.M., the incidence of BA in the Republic of Uzbekistan is on average 1-10000-1/15000. In the distribution of obstructive cholestasis in children, it was found that girls and boys meet in the ratio of 1.5/1.0, while other sources indicate 4:1. According to Aliev M.M. and the co-authors, the difference between girls and boys is not significant. In general, the assessment of the epidemiological situation of obstructive cholestasis in children is a complex sociological investigation, depending on the use of specialized research projects or equivalent applications. However, despite the recommended tests, the diagnosis of obstructive cholestasis continues to be delayed, which significantly worsens the results of their treatment.

Maqola ma’lumotlari
MualliflarALIYEV Mahmud Muslimovich, NEMATJONOV Farruh Zokirjon ogli, TUYCHIEV Golibjon Ormonovich, YULDASHEV Rustam Zafarjonovich
JurnalJournal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali
Nashr sanasi2023-02-07
Jild7
Son6
TilO‘zbek

Kalit so‘zlar

обструктивный холетсаз, билиарная атрезия, кистозная трансформация обшего желчного протока, цирроз печени, obstructive jaundice, biliary atresia, bile duct cystic transformations, liver cirrhosis, обструктив холестаз, билиар атрезия, умумий ўт йўли кистоз трансформацияси, жигар циррози.

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