Objective: To determine the effect of albendazole on the viability of protoscolexes and the frequency of relapses of echinococcal liver disease. Methods: The study was conducted in the surgical department of the multidisciplinary clinic of the Samarkand State Medical University, for 4 years from 2014 to 2017, with further follow-up for 5 years. The study included 86 cases in the age group of 17-66 years. The patients were divided into two groups of 43 people each. In the comparison group, patients were directly operated on, while in the main group, patients were prescribed albendazole for 12 weeks before surgery, followed by a postoperative course for 12 weeks. Results: Among patients treated with albendazole, no patient had viable cysts at the time of surgery compared to 93.1% of patients who did not receive albendazole before surgery (P<0.01). In patients not treated with albendazole, the relapse rate was 18.6%, while in patients treated with albendazole, no relapse was observed (P≤0.05). Conclusions: We concluded that albendazole is an effective adjuvant therapy in the treatment of Echinococcal liver disease.
| Mualliflar | KURBANIYAZOV Zafar Babajanovich, RAXMANOV Qosim Erdanovich, ANARBOEV Sanjar Alisherovich, MIZAMOV Furkat Ochilovich, MAHRAMKULOV Zafar Mamirkulovich |
|---|---|
| Jurnal | Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali |
| Nashr sanasi | 2022-12-11 |
| Jild | 7 |
| Son | 5 |
| Til | Rus |
эхинококкоз печени, альбендазол, профилактика, рецидив, liver echinococcosis, albendazole, prevention, relapse., jigar exinokokkozi, al'bendazol, kasallik qaytalanishini oldini olish, kasallik qaytalanishi.
To determine the effect of the morphological form of echinococcal cysts on the incidence of recurrence of the disease, we conducted a retrospective analysis of the operation protocols and determined that in 93…
Objective: The aim of the study is to improve the quality of treatment of patients with liver echinococcosis by using albendazole as a local germicide. Material and research methods. The clinical study consisted of 87…
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The results of morphological studies of 368 patients with thyroid nodules were analyzed. According to the results of the study, it was determined that PTAB is the only minimally invasive method of preoperative…
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